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Optimal treatment for patients with solid tumours in Europe through Artificial intelligence

Objective

OPTIMA is a multi-stakeholder-led consortium with the vision that each and every patient should have access to the most up-to-date individualised treatments and to innovative therapies. In that perspective, we will design, develop and deliver the first interoperable and GDPR compliant European real-world oncology data and evidence generation platform, along with decision support toolsets for prostate, lung and breast cancer. By designing this platform from the onset based on the needs of the clinicians and patients in an inclusive and sustainable way, OPTIMA aims to strengthen shared decision-making based on innovative data and AI-driven technology and tools.

To achieve our vision, we have united the key partners from other data-driven European wide oncology initiatives (PIONEER, EHDEN, HARMONY) in our project along with Europes leading clinicians in the fields of breast, prostate and lung cancer that all have leading roles in medical societies such as ERS, ESMO, and EAU. At the core of the OPTIMA project are the major guideline offices of the three indications, whilst the project is further strengthened by patient advocacy groups, well-known academic partners and 6 SMEs as partners covering the needed expertise to implement OPTIMA successfully.

The platform will build on existing open source solutions such as the OMOP-CDM, tranSMART and OHDSI ATLAS whilst developing novel AI models based on federated learning to facilitate knowledge discovery. At the start of the project, we will already have access to datasets covering over 200M people in Europe, along with data from high quality patient cohorts for AI model building. Moreover, the platform will be hosted in-kind on existing infrastructure provided by Helmholtz Institute in Germany. Finally, OPTIMA envisions sustainability of its platform through a value-based approach with various business models for commercial users.

Call for proposal

H2020-JTI-IMI2-2020-23-two-stage
See other projects for this call

Coordinator

STICHTING EUROPEAN UROLOGICAL FOUNDATION
Address
Mr. E.n. Van Kleffenstraat 5
6842 CV Arnhem
Netherlands
Activity type
Other
EU contribution
€ 822 280

Participants (35)

LUNDS UNIVERSITET
Sweden
EU contribution
€ 71 000
Address
Paradisgatan 5C
22100 Lund
Activity type
Higher or Secondary Education Establishments
ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM
Netherlands
EU contribution
€ 561 257
Address
Dr Molewaterplein 40
3015 GD Rotterdam
Activity type
Higher or Secondary Education Establishments
ASSOCIATION EISBM
France
EU contribution
€ 884 000
Address
7 Parc Des Cedres 11 Rue Jean Marie Chevalier
69390 Vourles
Activity type
Research Organisations
THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN
United Kingdom
EU contribution
€ 613 424
Address
King's College Regent Walk
AB24 3FX Aberdeen
Activity type
Higher or Secondary Education Establishments
TARTU ULIKOOL
Estonia
EU contribution
€ 470 000
Address
Ulikooli 18
51005 Tartu
Activity type
Higher or Secondary Education Establishments
UNIVERSITA VITA-SALUTE SAN RAFFAELE
Italy
EU contribution
€ 50 125
Address
Via Olgettina 58
20132 Milano
Activity type
Higher or Secondary Education Establishments
QUEEN MARY UNIVERSITY OF LONDON
United Kingdom
EU contribution
€ 220 000
Address
327 Mile End Road
E1 4NS London
Activity type
Higher or Secondary Education Establishments
HELMHOLTZ-ZENTRUM DRESDEN-ROSSENDORF EV
Germany
EU contribution
€ 684 000
Address
Bautzner Landstrasse 400
01328 Dresden
Activity type
Research Organisations
HELIOS KLINIKUM EMIL VON BEHRING GMBH
Germany
EU contribution
€ 0
Address
Schwanebecker Chaussee 50
13125 Berlin
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
UPPSALA UNIVERSITET
Sweden
EU contribution
€ 550 875
Address
Von Kraemers Alle 4
751 05 Uppsala
Activity type
Higher or Secondary Education Establishments
THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
United Kingdom
EU contribution
€ 967 594
Address
Wellington Square University Offices
OX1 2JD Oxford
Activity type
Higher or Secondary Education Establishments
UNIVERSITAT WIEN
Austria
EU contribution
€ 433 130
Address
Universitatsring 1
1010 Wien
Activity type
Higher or Secondary Education Establishments
ISTITUTO EUROPEO DI ONCOLOGIA SRL
Italy
EU contribution
€ 50 000
Address
Via Filodrammatici 10
20121 Milano
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN
Germany
EU contribution
€ 40 000
Address
Geschwister Scholl Platz 1
80539 Muenchen
Activity type
Higher or Secondary Education Establishments
UNIVERSITY COLLEGE LONDON
United Kingdom
EU contribution
€ 98 590
Address
Gower Street
WC1E 6BT London
Activity type
Higher or Secondary Education Establishments
EUROPEAN ORGANISATION FOR RESEARCH AND TREATMENT OF CANCER AISBL
Belgium
EU contribution
€ 75 001
Address
Avenue E. Mounier 83
1200 Brussels
Activity type
Research Organisations
INSTITUT DE CANCEROLOGIE DE L'OUEST
France
EU contribution
€ 90 000
Address
15 Rue Andre Boquel, Cs10059
49100 Angers
Activity type
Research Organisations
UNIVERSITEIT MAASTRICHT
Netherlands
EU contribution
€ 300 000
Address
Minderbroedersberg 4
6200 MD Maastricht
Activity type
Higher or Secondary Education Establishments
FUNDACIO INSTITUT UNIVERSITARI PERA LA RECERCA A L'ATENCIO PRIMARIA DE SALUT JORDI GOL I GURINA
Spain
EU contribution
€ 200 416
Address
Gran Via De Les Corts Catalanes 587
08007 Barcelona
Activity type
Research Organisations
EUROPEAN RESPIRATORY SOCIETY
Switzerland
EU contribution
€ 126 750
Address
Avenue Sainte Luce 4
1003 Lausanne
Activity type
Other
DEUTSCHE KREBSGESELLSCHAFT EV
Germany
EU contribution
€ 99 993
Address
Kuno Fischer Strasse 8
14057 Berlin
Activity type
Research Organisations
EUROPEAN LUNG FOUNDATION
United Kingdom
EU contribution
€ 127 312
Address
Glossop Road 442
S10 2PX Sheffield
Activity type
Other
EUROPEAN CANCER PATIENT COALITION
Belgium
EU contribution
€ 75 000
Address
Rue Montoyer 40
1000 Bruxelles
Activity type
Other
TTOPSTART BV
Netherlands
EU contribution
€ 341 910
Address
Euclideslaan 1
3584 BL Utrecht
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
GMV SOLUCIONES GLOBALES INTERNET SAU
Spain
EU contribution
€ 744 353
Address
Calle Isaac Newton 11 Parque Tecnologico De Madrid
28760 Tres Cantos Madrid
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
INFORMATION TECHNOLOGY FOR TRANSLATIONAL MEDICINE (ITTM) SA
Luxembourg
EU contribution
€ 787 500
Address
27 Rue Henri Koch
4354 Esch Sur Alzette
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
SMART REPORTING GMBH
Germany
EU contribution
€ 398 250
Address
Brienner Strasse 11
80333 Munchen
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
OWKIN FRANCE
France
EU contribution
€ 299 962
Address
12 Rue Martel
75010 Paris
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
ARTTIC INNOVATION GMBH
Germany
EU contribution
€ 115 000
Address
Oskar-von-miller-ring 29
80333 Munchen
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
YDEAL.NET SOFTWARE LDA
Portugal
EU contribution
€ 162 275
Address
Rua Antero Andrade E Silva 52
4520-401 Mosteiro
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
PFIZER LIMITED
United Kingdom
EU contribution
€ 0
Address
Ramsgate Road
CT13 9NJ Sandwich
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
BAYER AKTIENGESELLSCHAFT
Germany
EU contribution
€ 0
Address
Kaiser-wilhelm-allee 1
51373 Leverkusen
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
AMGEN
Belgium
EU contribution
€ 0
Address
Telecomlaan 5-7
1831 Diegem
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
F. HOFFMANN-LA ROCHE AG
Switzerland
EU contribution
€ 0
Address
Grenzacherstrasse 124
4070 Basel
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
ABBVIE INC
United States
EU contribution
€ 0
Address
North Waukegan Road 1
60064 North Chicago Il
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)