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Focused Ultrasound Personalized Therapy for the Treatment of Depression (UPSIDE)

Project description

Novel stimulation and recording system for treatment-resistant depression patients

Major depressive disorder (MDD) is a mood disorder which can interfere with daily life, and it is a major contributor to the overall global disease burden. About one third of MDD patients do not respond to established treatments. What is more, reliable biomarkers for depression are needed as a diagnostic tool. The EU-funded UPSIDE project aims to address these issues. To that end, it will research and validate in vivo a hybrid neurotechnology consisting of an epidural focused ultrasound stimulator and a high-density epidural EEG recording system. Project work will lead to a demonstrator, paving the way for personalised treatments for treatment-resistant depression patients.

Coordinator

TECHNISCHE UNIVERSITEIT DELFT
Net EU contribution
€ 1 678 031,00
Address
Stevinweg 1
2628 CN Delft
Netherlands

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Region
West-Nederland Zuid-Holland Delft en Westland
Activity type
Higher or Secondary Education Establishments
Other funding
€ 1 678 031,00

Participants (4)

UNIVERSITEIT GENT
Belgium
Net EU contribution
€ 859 040,00
Address
Sint Pietersnieuwstraat 25
9000 Gent

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Region
Vlaams Gewest Prov. Oost-Vlaanderen Arr. Gent
Activity type
Higher or Secondary Education Establishments
Other funding
€ 859 040,00
UNIVERSITAETSKLINIKUM FREIBURG
Germany
Net EU contribution
€ 523 150,00
Address
Hugstetter Strasse 49
79106 Freiburg

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Region
Baden-Württemberg Freiburg Freiburg im Breisgau, Stadtkreis
Activity type
Higher or Secondary Education Establishments
Other funding
€ 523 150,00
NEWRONIKA SPA
Italy
Net EU contribution
€ 436 750,00
Address
Via Dante 4
20121 Milano

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Nord-Ovest Lombardia Milano
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 436 750,00
SILICONGATE LDA
Portugal
Net EU contribution
€ 652 950,00
Address
Rua Alfredo Allen 455-461
4200135 Porto

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Continente Norte Área Metropolitana do Porto
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 652 950,00

Partners (2)

Micro Systems Technologies Management GmbH
Germany
Net EU contribution
€ 0,00
Address
Sieversufer 7-9
12359 Berlin

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Region
Berlin Berlin Berlin
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
FOCUSED ULTRASOUND FOUNDATION
United States
Net EU contribution
€ 0,00
Other funding
€ 0,00