Therapeutic targets against post-traumatic stress disorder
Post-traumatic stress disorder (PTSD) may develop in people who have experienced a traumatic event. Although feelings of shock, fear, and stress will normally go away over time, people with PTSD experience symptoms for longer and lose their ability to go on with their daily lives. Scientists of the ERC-funded SECRET-DOCK project had previously identified a neurocircuit in the brain that sensitises one to stress. They propose that this pathway may serve as a starting point for the identification of therapeutic targets. Researchers will screen small molecules as potential inhibitors against proteins implicated in this pathway, which is responsible for PTSD.
Fields of science
- HORIZON.1.1 - European Research Council (ERC) Main Programme