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Transient inactivation of hypothalamic hormone release to prevent post-traumatic stress sensitization

Project description

Therapeutic targets against post-traumatic stress disorder

Post-traumatic stress disorder (PTSD) may develop in people who have experienced a traumatic event. Although feelings of shock, fear, and stress will normally go away over time, people with PTSD experience symptoms for longer and lose their ability to go on with their daily lives. Scientists of the ERC-funded SECRET-DOCK project had previously identified a neurocircuit in the brain that sensitises one to stress. They propose that this pathway may serve as a starting point for the identification of therapeutic targets. Researchers will screen small molecules as potential inhibitors against proteins implicated in this pathway, which is responsible for PTSD.

Coordinator

MEDIZINISCHE UNIVERSITAET WIEN
Net EU contribution
€ 150 000,00
Address
Spitalgasse 23
1090 Wien
Austria

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Region
Wien Wien
Activity type
Higher or Secondary Education Establishments
Other funding
No data