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Alternative gene ends: the crosstalk of RNA cleavage and transcription termination

Project description

Gene expression regulation: the role of RNA cleavage

For a gene to be translated into protein, the intermediate messenger RNA must be correctly processed. This involves the process of 3’ end cleavage and polyadenylation, which facilitate exit from the nucleus, as well as the production of different isoforms, endowing multicellular organisms with spatial and temporal gene expression diversity. Scientists of the AlternativeEnds project, funded by the European Research Council, are interested to understand the underlying mechanism implicated in RNA cleavage and termination. Project activities will provide fundamental insight into alternative gene expression and offer the possibility of manipulating cleavage site selection for therapeutic purposes.

Coordinator

UNIWERSYTET IM. ADAMA MICKIEWICZA W POZNANIU
Net EU contribution
€ 1 444 600,00
Address
Ulica Henryka Wieniawskiego 1
61 712 Poznan
Poland

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Region
Makroregion północno-zachodni Wielkopolskie Miasto Poznań
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00

Participants (1)

INSTYTUT CHEMII BIOORGANICZNEJ POLSKIEJ AKADEMII NAUK
Poland
Net EU contribution
€ 49 250,00
Address
Noskowskiego 12-14
61 704 Poznan

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Region
Makroregion północno-zachodni Wielkopolskie Miasto Poznań
Activity type
Research Organisations
Other funding
€ 0,00