Project description
Predictive biomarkers of therapy response in colorectal cancer
Colorectal cancer starts in the colon or rectum and usually develops over time from precancerous polyps. Standard of treatment for locally advanced rectal cancer (LARC) involves neoadjuvant chemoradiotherapy (nCRT) followed by surgical resection of the tumour. However, clinical response to nCRT varies from complete clinical response to a lack of response. The mission of the EU-funded STEPUPIORS project is to identify prognostic and predictive biomarkers in LARC by analysing the molecular profile of patients at diagnosis and during treatment. Given that colorectal cancer is the third most common malignancy worldwide, the results aim to support evidence-based patient selection and modification of current treatment protocols, thus minimising adverse effects and overall treatment cost, and improving patients' quality of life.
Fields of science
Programme(s)
Funding Scheme
CSA - Coordination and support actionCoordinator
11000 Belgrade
Serbia
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Participants (4)
115 27 Athina
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08036 Barcelona
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Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.
08036 Barcelona
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1066 CX Amsterdam
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