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A European “shield” against colorectal cancer based on novel, more precise and affordable risk-based screening methods and viable policy pathways

Objective

With Colorectal Cancer (CRC) being accountable for 12.4% of all deaths due to cancer, and with only 14% of EU citizens participating in screening programmes, there is an urgent need for accurate, non-invasive, cost-effective screening tests based on novel technologies and an increased awareness on the disease and its detection. Furthermore, personalized approaches for screening are needed, to consider genetic and other socioeconomic variables and environmental stressors that lead to different onsets of the disease. ONCOSCREEN responds to these challenges by developing a risk-based, population-level stratification methodology for CRC, to account for genetic prevalence, socio-economic status, and other factors. It complements this methodology by a) developing a set of novel, practical, and low-cost screening technologies with high sensitivity and specificity, b) leveraging AI to improve existing methodologies for CRC screening, allowing for the early detection of polyps and provision of a personalized risk status stratification, and c) providing a mobile app for self-monitoring and CRC awareness raising. Furthermore, ONCOSCREEN develops an Intelligent Analytics dashboard for policy makers facilitating effective policy making at regional and national levels. Through a multi-level campaign, the above-mentioned solutions are tested and validated. For the clinical solutions specifically, a clinical validation study has been planned with the participation of 4100 enrolled patients/citizens. To ensure the adoption of the developed solutions by the healthcare systems, their cost-effectiveness and financial viability will be assessed. The 48-months duration project will be implemented by a multidisciplinary consortium comprising of 38 partners, including technical solutions providers, hospitals, Ministries of Health as policy makers, legal and ethics experts, Insurance companies, involving actively end-users/citizens in all phases of implementation through targeted workshops. This action is part of the Cancer Mission cluster of projects on ‘Prevention, including Screening.

Programme(s)

Coordinator

EXUS SOFTWARE MONOPROSOPI ETAIRIA PERIORISMENIS EVTHINIS
Net EU contribution
€ 1 015 625,00
Address
Theanous 15
118 54 Athens
Greece

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Region
Κεντρικός Τομέας Αθηνών Aττική Αττική
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00

Participants (39)

UNIVERSITAETSMEDIZIN DER JOHANNES GUTENBERG-UNIVERSITAET MAINZ
Germany
Net EU contribution
€ 757 500,00
Address
Langenbeckstrasse 1
55131 Mainz

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Region
Rheinland-Pfalz Rheinhessen-Pfalz Mainz, Kreisfreie Stadt
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
EREVNITIKO PANEPISTIMIAKO INSTITOUTO SYSTIMATON EPIKOINONION KAI YPOLGISTON-EMP
Greece
Net EU contribution
€ 625 750,00
Address
Patision 42
106 82 Athina

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Region
Κεντρικός Τομέας Αθηνών Aττική Αττική
Activity type
Research Organisations
Other funding
€ 0,00
FIRALIS
France
Net EU contribution
€ 691 500,00
Address
Rue Du Fort 35
68330 Huningue

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Grand Est Alsace Haut-Rhin
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
UNIVERSITATSKLINIKUM SCHLESWIG-HOLSTEIN
Germany
Net EU contribution
€ 198 492,50
Address
Ratzeburger Allee 160
23562 Lübeck

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Region
Baden-Württemberg Stuttgart Stuttgart, Stadtkreis
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
Third-party

Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.

UNIVERSITAET zu LUEBECK
Germany
Net EU contribution
€ 139 752,50
Address
Ratzeburger Allee 160
23562 Lubeck

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Region
Baden-Württemberg Stuttgart Stuttgart, Stadtkreis
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
LIETUVOS SVEIKATOS MOKSLU UNIVERSITETAS
Lithuania
Net EU contribution
€ 403 125,00
Address
A Mickeviciaus Gatve 9
44307 Kaunas

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Region
Lietuva Vidurio ir vakarų Lietuvos regionas Kauno apskritis
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
MEDIZINISCHE UNIVERSITAT GRAZ
Austria
Net EU contribution
€ 463 250,00
Address
Neue Stiftingtalstrasse 6
8010 Graz

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Region
Südösterreich Steiermark Graz
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
INSTITUTO PORTUGUES DE ONCOLOGIA DO PORTO FRANCISCO GENTIL, EPE
Portugal
Net EU contribution
€ 382 500,00
Address
Rua Antonio Bernardino Almeida
4200-072 Porto

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Region
Continente Norte Área Metropolitana do Porto
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Other funding
€ 0,00
INSTITUTUL ONCOLOGIC PROF. DR. ALEXANDRU TRESTIOREANU BUCURESTI
Romania
Net EU contribution
€ 268 750,00
Address
Soseaua Fundeni 252
022328 Bucharest

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Region
Macroregiunea Trei Bucureşti-Ilfov Bucureşti
Activity type
Research Organisations
Other funding
€ 0,00
TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY
Israel
Net EU contribution
€ 917 450,00
Address
Senate Building Technion City
32000 Haifa

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Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
UNIVERSIDADE DO MINHO
Portugal
Net EU contribution
€ 329 975,00
Address
Largo Do Paco
4704 553 Braga

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Region
Continente Norte Cávado
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
TILBURG UNIVERSITY- UNIVERSITEIT VAN TILBURG
Netherlands
Net EU contribution
€ 351 500,00
Address
Warandelaan 2
5037 AB Tilburg

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Region
Noord-Brabant Midden-Noord-Brabant
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
VLAAMSE INSTELLING VOOR TECHNOLOGISCH ONDERZOEK N.V.
Belgium
Net EU contribution
€ 408 310,00
Address
Boeretang 200
2400 Mol

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Region
Vlaams Gewest Prov. Antwerpen Arr. Turnhout
Activity type
Research Organisations
Other funding
€ 0,00
ETHNIKO KENTRO EREVNAS KAI TECHNOLOGIKIS ANAPTYXIS
Greece
Net EU contribution
€ 495 750,00
Address
Charilaou Thermi Road 6 Km
57001 Thermi Thessaloniki

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Region
Θεσσαλονίκη Κεντρική Μακεδονία Βόρεια Ελλάδα
Activity type
Research Organisations
Other funding
€ 0,00
INNOVATION SPRINT
Belgium
Net EU contribution
€ 281 250,00
Address
Rue Clos Chapelle-aux-champs 30 Bte 1.3.30
1200 Bruxelles

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Région de Bruxelles-Capitale/Brussels Hoofdstedelijk Gewest Région de Bruxelles-Capitale/ Brussels Hoofdstedelijk Gewest Arr. de Bruxelles-Capitale/Arr. Brussel-Hoofdstad
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
SCIENTIFIC ACADEMY FOR SERVICE TECHNOLOGY EV
Germany
Net EU contribution
€ 329 350,00
Address
Behlertstr 3a Haus 2b
14467 Postdam

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Brandenburg Brandenburg Potsdam
Activity type
Research Organisations
Other funding
€ 0,00
AINIGMA TECHNOLOGIES
Belgium
Net EU contribution
€ 298 750,00
Address
Kapeldreef 60
3001 Leuven

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Vlaams Gewest Prov. Vlaams-Brabant Arr. Leuven
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
CATALINK LIMITED
Cyprus
Net EU contribution
€ 246 875,00
Address
Charitinis Sakkada 5
1040 Nicosia

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Κύπρος Κύπρος Κύπρος
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
KONNEKT ABLE TECHNOLOGIES LIMITED
Ireland
Net EU contribution
€ 265 000,00
Address
Fdw House Blackthorn Business Park Coes Road
Dundalk Co Louth

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Ireland Eastern and Midland Mid-East
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
BEIA CONSULT INTERNATIONAL SRL
Romania
Net EU contribution
€ 191 250,00
Address
Street Poiana Narciselor 12 1st Floor Apartment 3 Sector 1
010158 Bucuresti

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Macroregiunea Trei Bucureşti-Ilfov Bucureşti
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
UNIVERSIDAD DE LA RIOJA
Spain
Net EU contribution
€ 245 000,00
Address
Avenida De La Paz 93
26006 La Rioja

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Region
Noreste La Rioja La Rioja
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
TIME.LEX
Belgium
Net EU contribution
€ 247 187,50
Address
Joseph Stevensstraat 7
1000 Brussel

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Région de Bruxelles-Capitale/Brussels Hoofdstedelijk Gewest Région de Bruxelles-Capitale/ Brussels Hoofdstedelijk Gewest Arr. de Bruxelles-Capitale/Arr. Brussel-Hoofdstad
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
CARR COMMUNICATIONS LIMITED
Ireland
Net EU contribution
€ 211 250,00
Address
24 Fitzwilliam Place
A96 PR60 Dublin

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Ireland Eastern and Midland Dublin
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
MINISTRY OF HEALTH
Greece
Net EU contribution
€ 207 500,00
Address
Aristotelous Street 17
Athina

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Region
Κεντρικός Τομέας Αθηνών Aττική Αττική
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Other funding
€ 0,00
PAGALBOS ONKOLOGINIAMS LIGONIAMS ASOCIACIJA
Lithuania
Net EU contribution
€ 143 750,00
Address
A. Mickeviciaus G. 9
44307 Kaunas

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Region
Lietuva Vidurio ir vakarų Lietuvos regionas Kauno apskritis
Activity type
Other
Other funding
€ 0,00
EUROPACOLON PORTUGAL- ASSOCIACAO DE LUTA CONTRA O CANCRO DO INTESTINO
Portugal
Net EU contribution
€ 115 000,00
Address
Estrada Interior Da Circunvalacao 6657 - 1 Sala 145
4200-172 Porto

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Region
Continente Norte Área Metropolitana do Porto
Activity type
Other
Other funding
€ 0,00
ELLINIKI ETAIREIA OGKOLOGIAS PEPTIKOU
Greece
Net EU contribution
€ 92 625,00
Address
Iera Odos 354
124 61 Chaidari Athina

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Region
Δυτικός Τομέας Αθηνών Aττική Αττική
Activity type
Other
Other funding
€ 0,00
EUROPAISCHE VEREINIGUNG DER GASTROINTESTINALEN ONKOLOGIE(EUROPEAN SOCIETY OF DIGESTIVE ONCOLOGY - ESDO)
Austria
Net EU contribution
€ 99 875,00
Address
Alser Strasse 4
1090 Wien

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Region
Wien Wien
Activity type
Research Organisations
Other funding
€ 0,00
FUNDATIA YOUTH CANCER EUROPE
Romania
Net EU contribution
€ 105 750,00
Address
Calea Manastur 42b
400372 Cluj Napoca

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Region
Macroregiunea Unu Nord-Vest Cluj
Activity type
Other
Other funding
€ 0,00
MEDIZINISCHE UNIVERSITAT INNSBRUCK
Austria
Net EU contribution
€ 338 750,00
Address
Christoph Probst Platz 1
6020 Innsbruck

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Region
Westösterreich Tirol Innsbruck
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
LIETUVOS RESPUBLIKOS SVEIKATOS APSAUGOS MINISTERIJA
Lithuania
Net EU contribution
€ 130 183,50
Address
Vilniaus G 33
LT 01506 Vilnius

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Region
Lietuva Sostinės regionas Vilniaus apskritis
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Other funding
€ 0,25
EY ADVISORY SPA
Italy
Net EU contribution
€ 228 125,00
Address
Via Meravigli 14
20123 Milano

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Region
Nord-Ovest Lombardia Milano
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS
Spain
Net EU contribution
€ 200 625,00
Address
Calle Serrano 117
28006 Madrid

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Region
Comunidad de Madrid Comunidad de Madrid Madrid
Activity type
Research Organisations
Other funding
€ 0,00
UNIVERSITE DE FRANCHE-COMTE
France
Net EU contribution
€ 260 625,00
Address
1 Rue Claude Goudimel
25000 Besancon

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Region
Bourgogne-Franche-Comté Franche-Comté Doubs
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
ROZENBAUM KONSULTING
Bulgaria
Net EU contribution
€ 511 625,00
Address
Ul 6ti Septemvri 13 B
1000 Sofia

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Югозападна и Южна централна България Югозападен София (столица)
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
GIE AXA
France
Net EU contribution
€ 220 625,00
Address
Avenue Matignon 23
75008 Paris

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Region
Ile-de-France Ile-de-France Paris
Activity type
Other
Other funding
€ 0,00
ASSOCIATION GERCOR
France
Net EU contribution
€ 352 500,00
Address
151 Rue Du Faubourg Saint Antoine
75011 Paris

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Region
Ile-de-France Ile-de-France Paris
Activity type
Research Organisations
Other funding
€ 0,00
LOUWEN ROGIER
Netherlands
Net EU contribution
€ 99 687,50
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
SANNE VOOGD
Netherlands
Net EU contribution
€ 99 687,50
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00