Objectif Protein molecules are highly flexible and can assume a large number of structurally slightly different states, called conformational substates. At physiological temperatures a molecule fluctuates among these conformational substates. Reducing the temperature the fluctuations die out at a critical temperature which is comparable to a glass transition. In proteins this critical temperature is at about 200K. The two additonal proposals from Estonia and Hungaria extend the original project in the following way: Optical spectroscopy is used in order to understand the inset of protein dynamics around the glass transition. Below the glass transtion the structural distributions are investigated by hole burning. Temperature Derivative Spectroscopy will be used to follow structural rearrangements after photoreactions. These spectroscopic methods have not been included into the original proposal. Besides of investigations on myoglobin, bacteriorhodopsin and the reaction center from photosynthetic bacteria are in the centre of interest of the additional proposals. Programme(s) IC-PECO/COPERNICUS - Scientific and technological cooperation between the European Community and European non-member countries, 1992- Thème(s) 0401 - CEEC participation in HUMAN CAPITAL & MOBILITY programme (NETWORKS) Appel à propositions Data not available Régime de financement CSC - Cost-sharing contracts Coordinateur Technische Universität München Contribution de l’UE Aucune donnée Adresse James-Franck-Straße 85748 Garching bei München Allemagne Voir sur la carte Coût total Aucune donnée Participants (2) Trier par ordre alphabétique Trier par contribution de l’UE Tout développer Tout réduire BIOLOGICAL RESEARCH CENTRE - HUNGARIAN ACADEMY OF SCIENCES Hongrie Contribution de l’UE Aucune donnée Adresse 62,Temesvari Krt. 62 6762 SZEGED Voir sur la carte Coût total Aucune donnée Institute of Physics Estonie Contribution de l’UE Aucune donnée Adresse 142,Riia 2400 Tartu Voir sur la carte Coût total Aucune donnée
