Objetivo The main objective of this project is to standardise the available assay protocols, and to identify the various methodological problems, thus providing guidelines for the use of 32P-postlabelling in detecting carcinogen-DNA adducts so that this procedure can be rationally applied for monitoring human exposure to environmental carcinogens.Through a series of collaborative studies and brain-storming sessions the project will enable :1) to provide users of postlabelling methods in various fields with standardized protocols;2) to improve the methods of identification of individuals in cancer epidemiology who, due to their increased exposure to carcinogens or due to their inherited susceptibility, are at increased risk of developing cancer;3) to assess the effectiveness of measures to reduce exposure to carcinogens in the work place and4) to determine the extent to which the use of biomarkers such as DNA adducts are quantitative indicators of cancer risk in humans. Ámbito científico natural sciencesbiological sciencesgeneticsDNAmedical and health scienceshealth sciencespublic healthepidemiologymedical and health sciencesclinical medicineoncology Programa(s) FP3-ENV 1C - Specific research and technological development programme (EEC) in the field of the environment, 1990-1994 Tema(s) 040204 - Risks to health and the environment from chemical substances Convocatoria de propuestas Data not available Régimen de financiación CSC - Cost-sharing contracts Coordinador Centre International de Recherche sur le Cancer Aportación de la UE Sin datos Dirección 150 cours Albert Thomas 69372 Lyon Francia Ver en el mapa Coste total Sin datos Participantes (1) Ordenar alfabéticamente Ordenar por aportación de la UE Ampliar todo Contraer todo INSTITUTE OF CANCER RESEARCH : ROYAL CANCER HOSPITAL Reino Unido Aportación de la UE Sin datos Dirección Cotswold Road 15 SM2 5NG Sutton Ver en el mapa Coste total Sin datos
