The significance of bronchial hypersensitivity as an early symptom of obstructive respiratory disease in underground miners subject to chronic exposure

Ziel

The crucial question is how much higher the incidence of obstructive respiratory disease is in miners underground whose bronchial system has been proved to be hypersensitive by the methacholine provocation test and how bronchial hypersensitivity, once ascertained, develops over the long term.

In the next four years 1400 miners are to be examined in the course of the regular two-yearly medicals. The clinical examination is - as previously - to be carried out using the standardized questionnaire.

METHODS AND MEANS BY WHICH THE AIMS ARE TO BE ACHIEVED

Whole-body plethysmographic measurements of the airway resistance and the intrathoracic gas volume are to be taken, an inhalation concentration test with 0.35% methacholine solution and a spirometric test of the VC, FVC, FEV1 and the flow-volume curve (MEF 75, MEF 50 and MEF 25) are to be carried out an all the subjects. The results will be analysed by a central computer using specially developed software.

Programm/Programme

ECSC-MEDRES 5C - Fifth medical research programme (ECSC) "Protection of workers against risks arising from work in the coal and steel industries", 1988-1992

Thema/Themen

Data not available

Aufforderung zur Vorschlagseinreichung

Data not available

Finanzierungsplan

CSC - Cost-sharing contracts

Koordinator

Berufsgenosschaftliches Forschungsinstitut für Arbeitsmedizin (BGFA)

EU-Beitrag

Keine Daten

Adresse

Bürkle-de-la-Camp-Platz 1
44789 BOCHUM
Deutschland

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