Objective While there is considerable information about radon-induced lung cancer risks from a range of epidemiological studies of underground miners, there are uncertainties about the assessment of risks arising from radon exposures in dwellings. The overall objectives of the project are to obtain direct information on the risk of lung cancer from indoor radon exposure by conducting epidemiological studies in several European countries, and to improve the quantification of these risks by performing a pooled analysis of these and other European studies. Three ongoing case-control studies will be completed. These are being performed in: (i) the Ardennes-Eifel region, where Belgian, French and German partners in collaboration with Luxembourg colleagues are collecting data for about 1200 lung cancer cases and 2400 controls; (ii) Southwest England, where data on nearly 1000 cases and over 3000 controls will be analysed; (iii) Brittany, Massif Central and Languedoc Rousillon in France, where ultimately about 600 cases and 1200 controls will be included. Radon measurements will also be made for subjects in recent case-control studies of lung cancer among never-smokers in Sweden. Together with data from earlier Swedish studies, a total of 480 never-smoking cases and 1900 controls will be obtained. These and other European studies will be included in a pooling exercise. Following the preparation of a protocol, the collaborators will transfer their data to a Secretariat which will be responsible for the organisation and execution of the pooled analysis; full involvement of the collaborators will be sought throughout the process. Although not yet finalised, the total number of lung cancer cases is likely to be of the order of 10,000. The pooled analysis should allow risks from indoor radon to be estimated more precisely and permit investigation of interactions with factors such as smoking. Programme(s) EAEC-NFS 2 - Specific research and training programme in the field of nuclear safety and safeguards, 1994-1998 Topic(s) 040104 - Epidemiology and exposed populations Call for proposal Data not available Funding Scheme CSC - Cost-sharing contracts Coordinator NATIONAL RADIOLOGICAL PROTECTION BOARD EU contribution No data Address OX11 0RQ Didcot,harwell,chilton United Kingdom See on map Total cost No data Participants (5) Sort alphabetically Sort by EU Contribution Expand all Collapse all Commissariat à l'Energie Atomique (CEA) France EU contribution No data Address Centre d'etudes de fontenay-aux-roses 92265 Fontenay-aux-roses See on map Total cost No data GENT UNIVERSITY Belgium EU contribution No data Address 86,proeftuinstraat 86 9000 Gent See on map Total cost No data GSF-RESEARCH CENTER FOR ENVIRONMENT AND HEALTH Germany EU contribution No data Address Ingolstaedter landstrase 1 85764 Oberschleissheim See on map Total cost No data Imperial Cancer Research Fund United Kingdom EU contribution No data Address The radcliffe infirmary, gibson building OX2 6HE Oxford See on map Total cost No data KAROLINSKA INSTITUTE Sweden EU contribution No data Address Nobels vaeg, 13 171 77 Stockholm See on map Total cost No data