Obiettivo Binding of Ca2+ ions to intracellular target proteins controls a variety of important cell functions. The concentration of intracellular calcium acts as a second messenger. The processes that control the concentration of intracellular calcium are related in nerve, cardiac and vascular cells. The Ca2+ regulation of the following molecular events will be studied: gene expression, cell growth, cell differentiation and ageing; cell respiration by Ca2+ control of oxidative phosphorylation in the mitochondria; Ca2+ activation of contraction by Ca2+ binding to troponinC or to calmodulin; Ca2+ control of cell excitability by Ca2+ binding to membrane channels; and neuronal plasticity through Ca2+ control of presynaptic neurotransmitter release. The results will extend the present understanding of important molecular events in the cardiovascular and the central neuronal system. Programma(i) IC-INTAS - International Association for the promotion of cooperation with scientists from the independent states of the former Soviet Union (INTAS), 1993- Argomento(i) 43 - Physiology and Fundamental Medical Science Invito a presentare proposte Data not available Meccanismo di finanziamento Data not available Coordinatore Universität Köln Contributo UE Nessun dato Indirizzo Robert-Koch-Straße 39 50924 Köln Germania Mostra sulla mappa Costo totale Nessun dato Partecipanti (3) Classifica in ordine alfabetico Classifica per Contributo UE Espandi tutto Riduci tutto Eberhard-Karls-Universität Tübingen Germania Contributo UE Nessun dato Indirizzo 72076 Tübingen Mostra sulla mappa Costo totale Nessun dato National Academy of Sciences of Ukraine Ucraina Contributo UE Nessun dato Indirizzo GSP 252601 Kiev Mostra sulla mappa Costo totale Nessun dato University of Liverpool Regno Unito Contributo UE Nessun dato Indirizzo L69 3BX Liverpool Mostra sulla mappa Costo totale Nessun dato
