Obiettivo Currently available live vaccines used for medical prophylaxis of brucellosis present serious side effects, which restrict their use and require good managing procedures for sanitary authorities and the farmer to obtain a definitive eradication. The most crucial of these drawbacks is that the live vaccines, whilst attenuated, still remain fully virulent for man. In addition, the vaccination is not fully efficacious and interferes with the diagnosis of field infection. Because of the continuing European incidence of brucellosis in animals and man, the development of a safe and efficacious vaccine that do not possess these disadvantages but which does stimulate protective immunity against the major pathogens of the genus Brucella is highly desirable and justified. The objectives of the proposal are to obtain well defined (rationally) attenuated vaccine strains or an efficient DNA vaccine that are immunologically distinguishable from natural infection and do not present the drawbacks if of existing vaccines. Campo scientifico natural sciencesbiological sciencesgeneticsDNAmedical and health sciencesbasic medicinepharmacology and pharmacypharmaceutical drugsvaccines Programma(i) FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002 Argomento(i) 1.1.1.-2. - Key action Control of Infectious Diseases Invito a presentare proposte Data not available Meccanismo di finanziamento CSC - Cost-sharing contracts Coordinatore INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE Contributo UE Nessun dato Indirizzo Rue de Tolbiac, 101 75654 PARIS Francia Mostra sulla mappa Costo totale Nessun dato Partecipanti (5) Classifica in ordine alfabetico Classifica per Contributo UE Espandi tutto Riduci tutto CENTRE D'ETUDE ET DE RECHERCHES VETERINAIRES ET AGROCHIMIQUES Belgio Contributo UE Nessun dato Indirizzo 99,Rue Groeselenberg 99 1180 BRUXELLES Mostra sulla mappa Costo totale Nessun dato FACULTES UNIVERSITAIRES NOTRE-DAME DE LA PAIX DE NAMUR Belgio Contributo UE Nessun dato Indirizzo Rue de Bruxelles 61 NAMUR / NAMEN Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato THE MINISTER OF AGRICULTURE, FISHERIES AND FOOD Regno Unito Contributo UE Nessun dato Indirizzo Smith Square 17, Nobel House SW1P 3JR LONDON Mostra sulla mappa Costo totale Nessun dato UNIVERSIDAD DE CANTABRIA Spagna Contributo UE Nessun dato Indirizzo Pabellon de Gobierno, Avenida de los Castros s/n 39005 SANTANDER Mostra sulla mappa Costo totale Nessun dato VETOQUINOL SA Francia Contributo UE Nessun dato Indirizzo Rue du Chêne Saint Anne 34 70204 LURE Mostra sulla mappa Costo totale Nessun dato
