CORDIS
EU research results

CORDIS

English EN

Hepatitis c virus (hcv) : prevention and treatment of infection and disease

Objective

The overall objective of this cluster is to contribute to the development of preventive and therapeutic vaccines against hepatitis C virus (HCV) infection. For this objective an in depth understanding of protective antiviral immune responses is essential by acquiring knowledge on mechanisms associated with HCV replication, assembly and fundamental knowledge on HCV specific immune responses in natural infections. A key element in the development of a vaccine is the choice of a delivery system capable to induce a humoral and/or a cellular-mediated protective immune response. The networks in this cluster proposal have strong, worldwide recognized expertise and have all parameters to monitor the planned analysis from fundamental in vitro studies to the evaluation of vaccine candidates in non-human primates. The basic strength of the Cluster is to re-unite expertise and unique systems that will allow a solid basis for the definition of clinical trials.

Coordinator

LEIDEN UNIVERSITY

Address

22,Albinusdreef 22 P4-25
2300 Rc Leiden

Netherlands

Participants (15)

Sort alphabetically

Expand all

ALBERT-LUDWIGS-UNIVERSITAET FREIBURG

Germany

BERNA BIOTECH LTD

Switzerland

BIOMERIEUX ALLIANCE SA

France

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE

France

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE

France

FOUNDATION BIOMEDICAL PRIMATE RESEARCH CENTRE

Netherlands

GSF-RESEARCH CENTER FOR ENVIRONMENT AND HEALTH

Germany

INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE

France

JOHANNES GUTENBERG UNIVERSITAET MAINZ

Germany

KAROLINSKA INSTITUTE

Sweden

LUDWIG-MAXIMILIANS UNIVERSITY OF MUNICH

Germany

THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD

United Kingdom

UNIVERSIDAD DE NAVARRA

Spain

UNIVERSITA DEGLI STUDI DI BARI

Italy

UNIVERSITE DE PARIS V 'RENÉ DESCARTES'

France

Project information

Grant agreement ID: QLK2-CT-1999-00356

  • Start date

    1 March 2000

  • End date

    31 July 2004

Funded under:

FP5-LIFE QUALITY

  • Overall budget:

    € 7 360 334

  • EU contribution

    € 4 098 030

Coordinated by:

LEIDEN UNIVERSITY

Netherlands