Objectif Interesting new compounds have been isolated from marine sponges: e.g. cytotoxic compounds that may be used as anti-cancer drugs, antibiotics, anti-viral agents and compounds with anti-inflammatory and cardiovascular properties. Biotechnological production under well defined conditions of sponge biomass is a necessary step towards commercialization of these potentially interesting products. So far, no primary-cell suspension cultures showed growth. Sponge cells need cell-cell contact to proliferate. In order to obtain axenic sponge tissue cultures, sponges can be dissociated, cleaned from other organisms than the sponge cells and reaggregated. Primary cell cultures can be reaggregated to strong spherical aggregates, primmorphs. The goal is to develop a process for in vitro cultivation of marine sponges for the production of biological active compounds. Sponges will be grown as primmorphs in bioreactors. Optimisation of the growth of and isolation of bioactive components from these primmorphs is the main objective of the project. A process design (including the market analysis) will be made. Champ scientifique engineering and technologyenvironmental biotechnologybioremediationbioreactorsmedical and health sciencesbasic medicinepharmacology and pharmacypharmaceutical drugsantibioticsagricultural sciencesagricultural biotechnologybiomass Programme(s) FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002 Thème(s) 1.1.1.-3. - Key action The "Cell factory" Appel à propositions Data not available Régime de financement CSC - Cost-sharing contracts Coordinateur WAGENINGEN UNIVERSITY Contribution de l’UE Aucune donnée Adresse Costerweg 50 WAGENINGEN Pays-Bas Voir sur la carte Liens Site web Opens in new window Coût total Aucune donnée Participants (4) Trier par ordre alphabétique Trier par contribution de l’UE Tout développer Tout réduire JOHANNES GUTENBERG UNIVERSITAET MAINZ Allemagne Contribution de l’UE Aucune donnée Adresse 6,Duesbergweg 6 55099 MAINZ Voir sur la carte Coût total Aucune donnée KLINIPHARM DIA MED VERTRIEBS GMBH Allemagne Contribution de l’UE Aucune donnée Adresse Hochstrasse 2 60313 FRANKFURT AM-MAIN Voir sur la carte Coût total Aucune donnée NATIONAL INSTITUTE OF CHEMICAL PHYSICS AND BIOPHYSICS Estonie Contribution de l’UE Aucune donnée Adresse 23,Akademia Tee 23 12618 TALLINN Voir sur la carte Coût total Aucune donnée NATIONAL RESEARCH COUNCIL OF ITALY Italie Contribution de l’UE Aucune donnée Adresse Piazzale Aldo Moro 7 00185 ROMA Voir sur la carte Coût total Aucune donnée