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Detection of illegal drugs by isotope ratio mass spectrometry : improvement of sensitivity, widening of applicability and development of tests and reference data (ISOTRACE)

Objective

The fight against unlawful use of substances by athletes in sport and to animals used for human food chain are European priorities. Recently, the administration of steroid hormones with the same chemical structure as the natural ones is prevalent attempting to prevent detection of their misuse. Isotope Ratio Mass Spectrometry is appearing as a definitive tool for detection of this fraud. This project aims to increase the sensitivity needed to detect some of the recent abused compounds by measuring their 13C content and also to expand the applicability by measuring 2H content as a new diagnostic test. Developments will be leaded by public research groups experienced in drug testing together with a SME manufacturer for isotope ratio instrumentation. Applicability will be confirmed by additional testing laboratories. Outcomes will be instrumental prototypes, supporting data, publications and applicability for the next European Olympic Games.

Funding Scheme

CSC - Cost-sharing contracts

Coordinator

FUNDACIO IMIM
Address
Carrer Del Doctor Aiguader 80
08003 Barcelona
Spain

Participants (7)

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
France
Address
Autor.lyon-vienne,echangeur De Solaize
69390 Vernaison
INSTITUT MUNICIPAL D'ASSISTENCIA SANITARIA
Spain
Address
Carrer Del Doctor Aiguader 80
08003 Barcelona
NATIONAL INSTITUTE OF PUBLIC HEALTH AND ENVIRONMENT
Netherlands
Address
9,Antonie Van Leeuwenhoeklaan 9
3720 BA Bilthoven
OLYMPIC ATHLETIC CENTER OF ATHENS "SPYROS LOUIS"
Greece
Address
Kifissias 37
15123 Athenes-athina
PDZ EUROPA LTD
United Kingdom
Address
Elizabeth House 1, Royal Court, Tatton Street
WA16 6EN Knutsford
THE PROVOST, FELLOWS AND SCHOLARS OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN HEREINAFTER TRINITY COLLEGE DUBLIN
Ireland
Address
Belfield
4 Dublin
UNIVERSITY OF GLASGOW
United Kingdom
Address
Rankine Avenue
G75 0QF Glasgow