The project will for the first time undertake a comprehensive, in-depth evaluation of the beneficial roles and interactions of long-chained n-3 polyunsaturated fatty acids (n-3 LC PUFA) and 5-methyl-tetra-hydro-folate (5-MTHF) in cardiovascular health and infant development. It will investigate effects on CVD-related biomarkers and on the development of infants, when mothers had been supplemented during pregnancy. The information obtained will allow the development of various functional foods enriched with stable forms of these nutraceuticals, thereby providing an optimum taste profile and ensuring consumer acceptability. These functional foods will help to reduce the deficit between current intakes of these nutrients and their actual requirement for optimal health in a large proportion of the European population. The products will also be of high commercial value to the European food industry.