Cord blood cells, collected at birth, have new interesting properties which can be used for treatment of leukemias and other malignant diseases and also for the treatment of genetic or acquired hematological disorders. Cord blood banks have been established worldwide, and thanks to international collaboration, results of allogeneic unrelated cord blood transplants have been analysed. From these studies, it can be concluded that this new source of hematopoietic stem cells is a life-saving therapy used in a large variety of potentially fatal diseases mostly in children. The objectives of this proposal are to better characterise hematopoietic stem cells present in cord blood and take advantage of the immaturity and proliferative characteristics of the cells to treat a large variety of malignant, immunological, genetic and infectious diseases. The proposal will be divided in 4 components: hematopoiesis, immunology, clinical applications of cord blood cells and interface between transplant centres and cord blood banks.
Funding SchemeTHN - Thematic network contracts
08907 Hospitalet Del Llobregat
NW3 2QG London