CORDIS
EU research results

CORDIS

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Development of molecular vaccines and diagnostics for the control of tropical theileriosis

Project information

Grant agreement ID: ICA4-CT-2000-30020

  • Start date

    1 July 2000

  • End date

    31 December 2003

Funded under:

FP5-INCO 2

  • Overall budget:

    € 813 000

  • EU contribution

    € 813 000

Coordinated by:

UNIVERSITY OF YORK

United Kingdom

Objective

The aim of the project is to develop a subunit vaccine and novel life-cycle stage specific diagnostics for T. annulated. Protective immunity involves effectors directed at 3 life-cycle stages (sporozoite, merozoite & schizont). Using a novel delivery system six available secreted schizont antigens plus an existing sporozoite & merozoite surface antigen will be tested for protective capacity. Previously noted synergism in protection between the sporozoite & merozoitesurface antigen will be further evaluated. Additional secreted schizont antigens will be isolated. Analysis of the immune response to these antigens will drive the design of further protection trials as will the role of antigenic diversity. Rapid, simple fondant serological diagnostics will be developed & used for epidemiological analysis and to assess the efficacy of novel subunit and existing live vaccines.

Leaflet | Map data © OpenStreetMap contributors, Credit: EC-GISCO, © EuroGeographics for the administrative boundaries

Coordinator

UNIVERSITY OF YORK

Address

Heslington
York

United Kingdom

Participants (5)

ADNAN MENDERES UNIVERSITY

Turkey

ECOLE NATIONALE DE MEDICINE VETERINAIRE

Tunisia

INSTITUT PASTEUR DE TUNIS

Tunisia

UNIVERSITY OF GLASGOW

United Kingdom

UTRECHT UNIVERSITY

Netherlands

Project information

Grant agreement ID: ICA4-CT-2000-30020

  • Start date

    1 July 2000

  • End date

    31 December 2003

Funded under:

FP5-INCO 2

  • Overall budget:

    € 813 000

  • EU contribution

    € 813 000

Coordinated by:

UNIVERSITY OF YORK

United Kingdom