Obiettivo The rationale for this project is given by the fact that the pharmaceutical industry is currently undergoing a significant change in strategy in preclinical drug development. Relevant advances are being made in the field of genome analysis with the onset of gene chip technologies permitting high throughput investigations and the use of miniature sample quantities. The same is happening for protease analysis and mass- spectrometry. We want to develop the "missing link" in high throughput testing: A highly controlled high-throughput bioreactor based on the use of engineered miniature in vitro tissue analogues. This will lead to the establishment of a firm correlation between genome, protease and catalytic expressions or biochemical function resulting in a complementary and more predictive picture of drug action. Campo scientifico medical and health sciencesbasic medicinepharmacology and pharmacydrug discoveryengineering and technologyenvironmental biotechnologybioremediationbioreactorsnatural scienceschemical sciencesanalytical chemistrymass spectrometrysocial scienceseconomics and businesseconomicssustainable economynatural sciencesbiological sciencesgeneticsgenomes Programma(i) FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002 Argomento(i) 1.1.1.-5. - Key action Sustainable Agriculture, Fisheries and Forestry Invito a presentare proposte Data not available Meccanismo di finanziamento CSC - Cost-sharing contracts Coordinatore NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY Contributo UE Nessun dato Indirizzo NTNU 7491 TRONDHEIM Norvegia Mostra sulla mappa Costo totale Nessun dato Partecipanti (2) Classifica in ordine alfabetico Classifica per Contributo UE Espandi tutto Riduci tutto AACHEN UNIVERSITY OF TECHNOLOGY Germania Contributo UE Nessun dato Indirizzo Eilfshornstrasse, 16 52056 AACHEN Mostra sulla mappa Costo totale Nessun dato CENTRE FOR RURAL RESEARCH Norvegia Contributo UE Nessun dato Indirizzo University Centre, NTNU Dragvoll 7491 TRONDHEIM Mostra sulla mappa Costo totale Nessun dato