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Anti-disease approach for immunological control of livestock trypanosomosis

Objective

Trypanomosis is a major constraint to livestock productivity in the developing world. The existing control options are not entirely satisfactory and there is little hope for a conventional vaccine. We propose an alternative immunological approach which aims at reducing the pathological consequences of trypanosome infection, through immunisation against parasite cytokine protease (Caps). Initial for Caps in pathology. The project will evaluate the effects of immunisation with recombinant trypanosome CPS on health and productivity of: ruminants. An important basic component is included, which aims at molecular and genetic characterisation the host. As Caps are major antigens in trypanosome-infected cattle, it is proposed to also evaluate the diagnostic potential of recombinant and. synthetic products.

Topic(s)

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Call for proposal

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Coordinator

CENTRE DE COOPERATION INTERNATIONALE EN RECHERCHE AGRONOMIQUE POUR LE DEVELOPPEMENT - CIRAD
EU contribution
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Address
10 rue Pierre Curie
97165 POINTE A PITRE
France

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Total cost
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Participants (4)