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Biokinetics and dosimetry of internal contamination

Objective

The assessment of doses and risks from radionuclide exposures is critically dependent on the development of reliable biokinetic and dosimetric models to represent the behaviour of radionuclides in the body and energy deposition in sensitive cells. This proposal from eleven EU partners has the objective of providing such models, targeting specific uncertainties, including: doses to regions of the gut and other tissues following radionuclide ingestion; the time-course of urinary and faecal excretion of radionuclides in relation to body content and intake; doses to newborn children from radionuclides transferred in breast-milk; and, consideration of dose distribution within tissues and cells. Experimental approaches to the improvement of models will include: human biokinetic studies using stable isotopes; animal studies to assess dose distribution in the gut; and in vitro studies of dose deposition in cells.

Funding Scheme

CSC - Cost-sharing contracts

Coordinator

INSTITUT DE RADIOPROTECTION ET DE SURETE NUCLEAIRE
Address
Rue Auguste Lemaire
92262 Fontenay Aux Roses
France

Participants (14)

BUNDESAMT FUER STRAHLENSCHUTZ
Germany
Address
1,Ingolstädter Landstraße 1
85764 Oberschleissheim
COMMISSARIAT A L'ENERGIE ATOMIQUE
France
Address

91680 Bruyeres-le-chatel
DELFT UNIVERSITY OF TECHNOLOGY
Netherlands
Address
Mekelweg 15
2629 JB Delft
GSF-RESEARCH CENTER FOR ENVIRONMENT AND HEALTH
Germany
Address
Ingolstaedter Landstrasse 1
85764 Oberschleissheim
INSTITUT FUER AEROSOL MEDIZIN INAMED GMBH
Germany
Address
Taunusstrasse 12
35285 Gemuenden (Wohra)
KAROLINSKA INSTITUTE
Sweden
Address
Nobels Vaeg, 13
171 77 Stockholm
NATIONAL RADIOLOGICAL PROTECTION BOARD
United Kingdom
Address

OX11 0RQ Didcot,harwell,chilton
ROSTOCK UNIVERSITY
Germany
Address
Universitaetsplatz 2-4
18051 Rostock
SWEDISH RADIATION PROTECTION INSTITUTE
Sweden
Address

171 16 Stockholm
TECHNOORG LINDA CO. LTD
Hungary
Address
Rozsa U. 24
1077 Budapest
THE UNIVERSITY OF MILANO
Italy
Address
Via Celoria 16
20133 Milano
UNIVERSITY OF BERNE
Switzerland
Address
5,Sidlerstrasse 5
3012 Bern
UNIVERSITY OF SALZBURG
Austria
Address
Hellbrunnerstrasse 34
5020 Salzburg
UNIVERSITY OF WALES CARDIFF
United Kingdom
Address
Park Place, Main Building
CF10 3TB Cardiff