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Resolution of the hiroshima neutron discrepancy and the impact of dosimetric uncertainties

Ziel

The project will investigate systematic and random errors associated with the A-bomb dosimetry, and assess their impact on cancer risk estimates. Fast neutron fluences in Hiroshima will be determined retrospectively by extremely sensitive accelerator mass spectrometry, to reassess neutron doses of the A-bomb survivors (LSS cohort), and resolve thereby the' neutron discrepancy' in Hiroshima, which is currently one of the major sources of uncertainty in the derivation of risk coefficients. The results will, together with updated information on y-ray dosimetry, serve as the basis for an appraisal of the impact of dosimetric changes and dosimetric random errors on risk coefficients for y-rays and neutrons and on their Lincertainties. Sources of uncertainty in the LSS other than systematic errors in Hiroshima neutron dose estimates, such as different types of random errors in dose estimates, and modelling uncertainties associated with projecting risks to low doses and over time, will be assessed. Consequent uncertainties in the cancer risk estimates derived from the LSS will be quantified in terms of different carcinogenesis models (empirical and mechanistic).

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Koordinator

LUDWIG-MAXIMILIANS UNIVERSITY OF MUNICH
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Schillerstrasse 42
80336 MUENCHEN
Deutschland

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