Development and evaluation of nucleic acid amplification methods for the detection of respiratory pathogens in community acquired pneumonia

Informations projet

NAACAP

N° de convention de subvention: QLK2-CT-2000-00294

Date de début 1 Octobre 2000

Date de fin 31 Mars 2004

Financé au titre de

• Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002

Coût total € 1 291 844,00

Contribution de l’UE € 1 191 106,00

Coordonné par

UNIVERSITAIRE INSTELLING ANTWERPEN - UNIVERSITEIT ANTWERPEN
Belgium

Objectif

This project will result in a number of rapid "real time" rnultiplex nucleic acid amplification tests (NAAT) covering the whole spectrum of causes of atypical pneumonia, and in algorithms for their application. Each of the four partners willing close collaboration develop part of the necessary tests, the combination ofwhich will result in NASBA (RNA targeted) and PCR (DNA targeted) multiplex tests. The participation of an industrial company is of crucial importance to solve technical problems. The tests will be cross-validated between the partners by these of proficiency panels. The tests developed will be clinically validated by application to significant numbers of thoroughly documented respiratory specimens collected by three of the partners. The analysis of the results will allow deciding on algorithms to be used for the etiologic diagnosis of CAP.

Champ scientifique

• medical and health sciences › clinical medicine › pneumology
• natural sciences › biological sciences › biochemistry › biomolecules › nucleic acids
• natural sciences › biological sciences › genetics › DNA
• natural sciences › biological sciences › genetics › RNA

Programme(s)

• FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002

Thème(s)

• 1.1.1.-2. - Key action Control of Infectious Diseases

Appel à propositions

Data not available

Régime de financement

CSC - Cost-sharing contracts

Coordinateur

UNIVERSITAIRE INSTELLING ANTWERPEN - UNIVERSITEIT ANTWERPEN

• Contribution de l’UE: Aucune donnée
• Adresse: Universiteitsplein 1 S3 ; 2610 WILRIJK (ANTWERPEN) ; Belgique
• Coût total: Aucune donnée

Participants (3)

BIOMERIEUX BV

Pays-Bas

• Contribution de l’UE: Aucune donnée
• Adresse: Boseind, 15 ; 5280 AB BOXTEL
• Coût total: Aucune donnée

LEIDEN UNIVERSITY

Pays-Bas

• Contribution de l’UE: Aucune donnée
• Adresse: 72,Rapenburg 70 ; 2311 EZ LEIDEN
• Coût total: Aucune donnée

UNIVERSITY OF WALES COLLEGE OF MEDICINE

Royaume-Uni

• Contribution de l’UE: Aucune donnée
• Adresse: Heath Park ; CF4 4XN CARDIFF
• Coût total: Aucune donnée