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European collaborative study on pregnant hiv-infected women and their children

Objective

Vertical transmission rates in Europe have decreased with the recent widespread introduction of interventions such as anti-retroviral therapy, elective caesarean section delivery and no breastfeeding. However, these interventions and changes tithe management of adult disease raise new and complex questions. The European Collaborative Study is a prospective cohort study of children born to HIV-infected women, set up in 1987 to clarify issues relating to HIV infection in pregnancy and childhood. To date 2600 mother-child pairs have been enrolled from 22 centres in European countries. Continued enrolment and follow-up are proposed to explore these new questions, including the issue of adverse effects resulting from exposure to prophylactic antiretroviral drugs, the impact of such exposure on timing of diagnosis and natural history of infected children and the quality of life of affected families, and continued monitoring of vertical transmission rates

Funding Scheme

CON - Coordination of research actions

Coordinator

UNIVERSITY COLLEGE LONDON
Address
30,Guilford Street 30
WC1N 1EH London
United Kingdom

Participants (16)

AZIENDA OSPEDALIERA AUTONOMA - SANT'ANNA - O.I.R.M. TORINO
Italy
Address
Via Ventimiglia, 3
10126 Torino (Turin)
CENTRE HOSPITALIER UNIVERSITAIRE SAINT-PIERRE
Belgium
Address
Rue Haute 322
1000 Bruxelles
HOSPITAL CLINIC BARCELONA
Spain
Address
Villaroel 170
08036 Barcelona
HOSPITAL DEL MAR
Spain
Address
Passeig Maritim 25-29
08003 Barcelona
HOSPITAL UNIVERSITARIO DE LA FE SEVASA
Spain
Address
Avenida De Campanar 21
46009 Valencia
HOSPITAL UNIVERSITARIO LA PAZ
Spain
Address
Paseo De La Castellana 261
28046 Madrid
HUDDINGE UNIVERSITY HOSPITAL
Sweden
Address

141 86 Huddinge
HUMBOLDT-UNIVERSITAET BERLIN
Germany
Address
Augustenburger Platz 1
13353 Berlin
IMPERIAL COLLEGE OF SCIENCE, TECHNOLOGY AND MEDICINE
United Kingdom
Address
Norfolk Place - St Mary's Hospital
W2 1PG London
MEDICAL UNIVERSITY OF WARSAW
Poland
Address
Wolska Street, 37
01-201 Warsaw
NATIONAL RESEARCH INSTITUTE FOR MOTHER AND CHILD
Poland
Address
Kasprazaka, 17 A
01-211 Warsaw
ODESSA OBLAST CLINICAL HOSPITAL
Ukraine
Address
Zabolotnogo Street, 26
65025 Odessa
ROYAL HOSPITAL FOR SICK CHILDREN
United Kingdom
Address
Chalmers Crescent 10
EH9 1TS Edinburgh
SECONDA UNIVERSITA DEGLI STUDI DI NAPOLI
Italy
Address
Via S Pansini, 5
80131 Napoli
UNIVERSITA DEGLI STUDI DI PADOVA
Italy
Address
Via Giustiniani 3
35128 Padova
UNIVERSITY OF GENOVA
Italy
Address
Largo R.benzi 10
16132 Genova