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Excitation-contraction coupling in the heart: regulmation of the calcium-release-chanel (crc) by post-translational modifications.

Obiettivo

The CRC plays a key role in excitation-contraction coupling, in the heart. The amount of Ca2+ that is released from the SR dictates the force of contraction. Elucidation of CRC regulation, at the molecular level, will enable us to design clinically-helpful agents that modulate cardiac contraction.

Invito a presentare proposte

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Coordinatore

MAX DELBRUCK CENTER FOR MOLECULAR MEDICINE
Contributo UE
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Indirizzo
Robert-Rössle-Straße 10
13122 BERLIN
Germania

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Costo totale
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