Objective Overactivity of the transcription factor NF-kB causes cancer and inflammations. This study will elucidate the regulation Nf-kB by the kinase TPL-2 using a combination of biochemical techniques with X-ray crystallography. Fields of science natural sciencesbiological sciencescell biologycell signalingnatural sciencesearth and related environmental sciencesgeologymineralogycrystallographymedical and health sciencesclinical medicineoncology Programme(s) FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002 Topic(s) 1.1.1.-4. - Key action Environment and Health Call for proposal Data not available Funding Scheme RGI - Research grants (individual fellowships) Coordinator MEDICAL RESEARCH COUNCIL EU contribution No data Address The Ridgeway Mill Hill NW7 1AA LONDON United Kingdom See on map Total cost No data