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Biochemical and structural basis of intracellular signalling by the tpl-2/nf-db complex

Objective

Overactivity of the transcription factor NF-kB causes cancer and inflammations. This study will elucidate the regulation Nf-kB by the kinase TPL-2 using a combination of biochemical techniques with X-ray crystallography.

Call for proposal

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Coordinator

MEDICAL RESEARCH COUNCIL
EU contribution
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Address
The Ridgeway Mill Hill
NW7 1AA LONDON
United Kingdom

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Total cost
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