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Quality in molecular genetic testing: development of certified reference materials (CRMGEN)

Project information

Grant agreement ID: G6RD-CT-2001-00581

  • Start date

    1 November 2001

  • End date

    31 October 2005

Funded under:

FP5-GROWTH

  • Overall budget:

    € 1 409 451

  • EU contribution

    € 1 284 910

Coordinated by:

NATIONAL UNIVERSITY OF IRELAND DUBLIN

Ireland

Objective

Molecular genetic testing involves the analysis of DNA for sequence changes. There has been a huge increase in the use of such tests in recent years. With such explosive growth in the application of a new technology for medical use, concerns about the quality and accuracy of the test results must arise. Reference materials (RMs) are used in laboratory analysis to ensure that tests are producing the correct result. Certified reference materials (CRMs) are RMs whose characteristics have been fully documented and validated. No CRMs are available for molecular genetic testing. This project will explore the production of various types of CRM for a range of molecular genetic tests. The prototype RMs will be validated by experienced genetics laboratories, and will be characterized by reference institutions before extensive field trials. The results will be used to develop guidelines for the production of CRMs for any molecular genetic test.

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Coordinator

NATIONAL UNIVERSITY OF IRELAND DUBLIN

Address

Our Lady'S Hospital For Sick Children, Crumlin
12 Dublin

Ireland

Participants (11)

COMMISSION OF THE EUROPEAN COMMUNITIES

Belgium

CYPRUS INSTITUTE OF NEUROLOGY AND GENETICS

Cyprus

INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE

France

KATHOLIEKE UNIVERSITEIT LEUVEN

Belgium

LEIDEN UNIVERSITY

Netherlands

NATIONAL RESEARCH INSTITUTE FOR MOTHER AND CHILD

Poland

THE CENTRAL MANCHESTER AND MANCHESTER CHILDREN'S UNIVERSITY HOSPITALS NATIONAL HEALTH SERVICE TRUST

United Kingdom

UNIVERSITY OF GLASGOW

United Kingdom

UNIVERSITY OF VIENNA

Austria

UNIVERSITY OF WUERZBURG

Germany

VILNIUS UNIVERSITY

Lithuania

Project information

Grant agreement ID: G6RD-CT-2001-00581

  • Start date

    1 November 2001

  • End date

    31 October 2005

Funded under:

FP5-GROWTH

  • Overall budget:

    € 1 409 451

  • EU contribution

    € 1 284 910

Coordinated by:

NATIONAL UNIVERSITY OF IRELAND DUBLIN

Ireland