Much salmonella’s prevention depends on early outbreak recognition through surveillance. The value of traditional methods such as phage-typing to discriminate strains for surveillance is established. Gene printing is used for outbreaks when enhanced sub-typing is needed. In many countries, however, certain salmonella stereotypes and phage-types predominate, and research on the routine use of new methods of subdivision is needed. The proposal will involve ten national reference laboratories in answering the key question about the extent of the improvement in surveillance system power obtained when gene printing is routinely used. Molecular sub-typing will provide information on the international distribution of antibiotic-resistant clones. The study will comprehensively explore the feasibility and cost of laboratories using common molecular subtypingmethods to conduct international surveillance in real time.
Funding SchemeCSC - Cost-sharing contracts
3720 BA Bilthoven
G21 3UR Glasgow
NW9 5HT London