Objective A wide range of common and lethal pathologies such as cardiovascular diseases, tumour growth and metastatic spread, are linked to the disruption of the angiogenic balance. The antiangiogenic treatments currently in clinical trials for cancer generally target a limited number of events involved in the angiogenic process. There is a pressing need to expand the number of therapeutic targets in this area. The consortium partner laboratories contribute expertise on a wide spectrum of cellular and in vivo models, providing a comprehensive representation of specific steps in neovascularization. These models will be processed by genomics analysis and promising genes will be pre-selected in vitro. The selected genes will be assessed and compared in the set of physiological and pathological models. This strategy will lead to the identification of novel critical genes and define their role in angiogenesis. Fields of science natural sciencesbiological sciencesgeneticsmedical and health sciencesclinical medicinecardiologycardiovascular diseasesmedical and health sciencesclinical medicineoncologymedical and health sciencesbasic medicinepathology Programme(s) FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002 Topic(s) 1.1.1.-7. - Chronic and degenerative diseases, cancer, diabetes, cardivascular diseases and rare diseases Call for proposal Data not available Funding Scheme CSC - Cost-sharing contracts Coordinator AVENTIS PHARMA RECHERCHE DEVELOPPEMENT S.A. EU contribution No data Address Quai Jules Guesde 13 94403 VITRY SUR SEINE France See on map Total cost No data Participants (4) Sort alphabetically Sort by EU Contribution Expand all Collapse all FLANDERS INTERUNIVERSITY INSTITUTE FOR BIOTECHNOLOGY VZW Belgium EU contribution No data Address 49,Herestraat 49 KUL / Campus Gasthuisberg 3000 LOUVAIN / LEUVEN See on map Total cost No data MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. Germany EU contribution No data Address Benekestrasse 2 61231 BAD NAUHEIM See on map Total cost No data TUMOR BIOLOGY CENTRE FREIBURG Germany EU contribution No data Address Breisacher Strasse 117 79106 FREIBURG (IN BREISGAU) See on map Total cost No data UNIVERSITY OF HELSINKI Finland EU contribution No data Address 3,Haartmaninkatu 8 00014 HELSINKI See on map Total cost No data