CORDIS
EU research results

CORDIS

English EN

Preparing for an influenza pandemic (FLUPAN)

Project information

Grant agreement ID: QLK2-CT-2001-01786

  • Start date

    1 September 2001

  • End date

    31 May 2007

Funded under:

FP5-LIFE QUALITY

  • Overall budget:

    € 2 435 150

  • EU contribution

    € 2 100 562

Coordinated by:

NATIONAL BIOLOGICAL STANDARDS BOARD

United Kingdom

Objective

Evidence from the Hong Kong chicken influenza outbreak has made us aware that we are ill prepared to produce conventional egg-grown influenza vaccines in response to a pandemic. This project will use reverse genetics to modify avian or swine influenza viruses, so that they are safe to use and grow well on mammalian cells. An MDCK or Vero cell vaccine will be produced from a highly pathogenic avian virus, modified so that it is attenuated. The vaccine will be evaluated pacifically and clinically. We will also produce a library of reagents from a variety of avian and swine viruses for use in eggs or cell culture vaccine manufacture and develop new techniques for monitoring transmission of animal viruses to man.

Leaflet | Map data © OpenStreetMap contributors, Credit: EC-GISCO, © EuroGeographics for the administrative boundaries

Coordinator

NATIONAL BIOLOGICAL STANDARDS BOARD

Address

Blanche Lane, South Mimms
En6 3qg Potters Bar

United Kingdom

Participants (9)

AVENTIS PASTEUR SA

France

CELLON SA

Luxembourg

HEALTH PROTECTION AGENCY

United Kingdom

ISTITUTO NAZIONALE PER LA FAUNA SELVATICA "A.GHIGHI"

Italy

ISTITUTO SUPERIORE DI SANITA

Italy

ISTITUTO ZOOPROFILATTICO SPERIMENTALE DELLA LOMBARDIA E DELL'EMILIA ROMAGNA "BRUNO UBERTINI"

Italy

UNIVERSITY OF BERGEN

Norway

UNIVERSITY OF READING

United Kingdom

VLA WEYBRIDGE

United Kingdom

Project information

Grant agreement ID: QLK2-CT-2001-01786

  • Start date

    1 September 2001

  • End date

    31 May 2007

Funded under:

FP5-LIFE QUALITY

  • Overall budget:

    € 2 435 150

  • EU contribution

    € 2 100 562

Coordinated by:

NATIONAL BIOLOGICAL STANDARDS BOARD

United Kingdom