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Early diagnosis of Alzheimer's disease and related dementia

Objective

Alzheimer's disease (AD) and related dementia are irreversible, degenerative disorders of the brain characterised by progressive cognitive decline, the loss of personality and finally death. Because of the impact on individuals and due to the enormous costs for health care and thus for society, these disorders present a major health problem to the EU. Treatment that can prevent, arrest and reverse degeneration and death of neurons is therefore urgently required. Prerequisite is the development of diagnostic tools that identify patients at an early pre-symptomatic stage. A consortium of 21 of the most experienced AD laboratories from Europe and beyond will carry out a research project integrating data from studies with tissue cultures and genetically modified animals into a clinical investigation of demented patients. A broad array of bio-technological methods will be used. Results of these studies will lead to diagnostic screening strategies combining genetic, path physiological and biomarker information.

Coordinator

VERUM - FOUNDATION FOR BEHAVIOUR AND ENVIRONMENT
Address
Pettenkoferstr. 33
80336 Muenchen
Germany

Participants (11)

EVOTEC NEUROSCIENCES GMBH
Germany
Address
Schnackenburgallee 114
22525 Hamburg
FACULTY OF MEDICINE/UNIVERSITY HOSPITAL GOETTINGEN
Germany
Address
Robert-koch-strasse 40
37075 Goettingen
FLANDERS INTERUNIVERSITY INSTITUTE FOR BIOTECHNOLOGY VZW
Belgium
Address
Rijvisschestraat 120
9052 Zwijnaarde
FONDAZIONE CAVALIERI OTTOLENGHI
Italy
Address
San Luigi Gonzaga Hospital, Regione Gonzole 10
10043 Orbassano
FUNDACION PARA LA INVESTIGACION MEDICA APLICADA
Spain
Address
Pintor Paret 5, Oficina F
31008 Pamplona
LUDWIG-MAXIMILIANS UNIVERSITY OF MUNICH
Germany
Address
Geschwister-scholl-platz 1
80539 Muenchen
RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG
Germany
Address
307,Im Neuenheimer Feld 307
69120 Heidelberg
UNIVERSITY COLLEGE LONDON
United Kingdom
Address
Queen Square
WC1N 3BG London
UNIVERSITY OF AVEIRO
Portugal
Address
Campo Universitario De Santiago
3810-193 Aveiro
UNIVERSITY OF ZURICH
Switzerland
Address
Lenggstrasse 31
8029 Zurich
UPPSALA UNIVERSITY
Sweden
Address
Sankt Olofsgatan 10 B
75105 Uppsala