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Semliki forest virus based therapeutic systems

Objective

SFV based systems are increasingly the virus vector systems of choice for production of recombinant proteins for research, therapy and diagnosis. They have also been used as the basis for vaccines for a number of pathogens and recent studies indicate that they could be important systems for gene therapy and cancer therapy. For each of these uses the current system has limitations, which could be modified by engineering the viral replicas gene and by targeting to specific cell types. Work on SFV systems has been an exclusively European effort and this project will combine the expertise of the principal EU laboratories. The aim is to research, design, engineer, and test and delivers a new generation of SFV systems for research, biotechnology, vaccination, gene therapy and cancer therapy. These systems will have many important uses in biology, medicine and veterinary medicine and make an important contribution to the quality of life in Europe and worldwide.

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Coordinator

University of Edinburgh

Address

Old College South Bridge
Eh1 1hn Edinburgh

United Kingdom

Participants (6)

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BIOPTION AB

Sweden

ESTONIAN BIOCENTRE

Estonia

KAROLINSKA INSTITUTE

Sweden

NATIONAL UNIVERSITY OF IRELAND, DUBLIN

Ireland

THE PROVOST, FELLOWS AND SCHOLARS OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN HEREINAFTER TRINITY COLLEGE DUBLIN

Ireland

UNIVERSITY OF HELSINKI

Finland

Project information

Grant agreement ID: QLK3-CT-2002-02052

  • Start date

    1 November 2002

  • End date

    31 October 2005

Funded under:

FP5-LIFE QUALITY

  • Overall budget:

    € 2 246 707

  • EU contribution

    € 2 223 957

Coordinated by:

University of Edinburgh

United Kingdom