CORDIS
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A bio-active cochlear implant for severe deafness

Project information

Grant agreement ID: QLG3-CT-2002-01563

  • Start date

    1 October 2002

  • End date

    31 December 2005

Funded under:

FP5-LIFE QUALITY

  • Overall budget:

    € 2 370 621

  • EU contribution

    € 1 997 493

Coordinated by:

UNIVERSITY OF TAMPERE

Finland

Objective

A cochlear implant (CI) is a neuro-prosthesis for severe deafness. Our main objective is to pharmacologically treat the auditory nerve after CI, to protect the nerve from implantation trauma and to re-grow its peripheral processes. This treatment should improve speech understanding, enhancing the life quality of the patient. Animal studies, and studies on human tissue samples, will be performed to determine the efficacy of neurotrophins and antioxidants in preserving the auditory nerve following deafness. Delivery systems will also designed to supply drugs at the time of CI. Safety, effectiveness and dosage will be investigated, leading eventually to the first human trials of NTF in the inner ear. The outcomes of the research will have implications for the pharmacological treatment of hearing loss, for the use of NTF to prevent neural degeneration in CNS and for other neuroprostheses.

Coordinator

UNIVERSITY OF TAMPERE

Address

4,Medisiinarinkatu 3
33014 Tampere

Finland

Participants (8)

BCI BIOABSORBABLE CONCEPTS OY

Finland

HANNOVER MEDICAL SCHOOL

Germany

KAROLINSKA INSTITUTE

Sweden

LEOPOLD-FRANZENS-UNIVERSITAET INNSBRUCK

Austria

MED-EL GMBH

Austria

TAMPERE UNIVERSITY OF TECHNOLOGY

Finland

UNIVERSIT DEGLI STUDI DI FERRARA

Italy

UPPSALA UNIVERSITY

Sweden

Project information

Grant agreement ID: QLG3-CT-2002-01563

  • Start date

    1 October 2002

  • End date

    31 December 2005

Funded under:

FP5-LIFE QUALITY

  • Overall budget:

    € 2 370 621

  • EU contribution

    € 1 997 493

Coordinated by:

UNIVERSITY OF TAMPERE

Finland