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Anchored cAMP signalling - implications for treatment of human disease

Project information

Grant agreement ID: QLK3-CT-2002-02149

  • Start date

    1 November 2002

  • End date

    31 December 2005

Funded under:

FP5-LIFE QUALITY

  • Overall budget:

    € 2 470 168

  • EU contribution

    € 1 700 000

Coordinated by:

UNIVERSITY OF OSLO

Norway

Objective

Signalling pathways and networks involving the signal compound cAMP are involved in major chronic diseases within the European community such as HIV, cancer, diabetes type II, cardiovascular disease, and genetic diseases such as diabetes incipidus and muscular dystrophies. However, no systematic approach has explored the therapeutic potential in targeting the cAMP signal pathway in conditions such as listed above with a dysregulated cAMP signal pathway. The focus of the research in the present proposal is to devise and test of therapeutic strategies based on understanding function of components of signalling networks involving the signal compound cAMP, the down-stream effectors, interaction with targeting molecules, and substrates. Specifically, work will be aimed at solving highly competitive and major tasks by joint effort leading to in vivo proof of principle experiments and drug development.

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Coordinator

UNIVERSITY OF OSLO

Address

Sognvannsveien 9
0317 Oslo

Norway

Participants (9)

BIAFFIN GMBH & CO KG

Germany

BIOLOG LIFE SCIENCE INSTITUTE, FORSCHUNGSLABOR UND BIOCHEMICA- VERTRIEB GMBH

Germany

FONDAZIONE TELETHON

Italy

FORSCHUNGSVERBUND BERLIN E.V.

Germany

GOETEBORG UNIVERSITY

Sweden

INSTITUT CURIE

France

LAURAS AS

Norway

UNIVERSITY OF GLASGOW

United Kingdom

UNIVERSITY OF KASSEL

Germany

Project information

Grant agreement ID: QLK3-CT-2002-02149

  • Start date

    1 November 2002

  • End date

    31 December 2005

Funded under:

FP5-LIFE QUALITY

  • Overall budget:

    € 2 470 168

  • EU contribution

    € 1 700 000

Coordinated by:

UNIVERSITY OF OSLO

Norway