Objective This project proposes to study the binding determinants and mechanism of the growth factor-receptor association by protein crystallography, docking, and biophysical analysis. The ultimate goal is the design of small molecules targeting these protein-protein interactions for therapeutically purposes. Fields of science natural sciencesbiological sciencesbiochemistrybiomoleculesproteinsproteomicsmedical and health sciencesbasic medicinemedicinal chemistrynatural sciencesearth and related environmental sciencesgeologymineralogycrystallography Programme(s) FP5-HUMAN POTENTIAL - Programme for research, technological development and demonstration on "Improving the human research potential and the socio-economic knowledge base" (1998-2002) Topic(s) Data not available Call for proposal Data not available Funding Scheme RGI - Research grants (individual fellowships) Coordinator THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE EU contribution No data Address 80,Tennis Court Road, 80 CB2 1GA CAMBRIDGE United Kingdom See on map Total cost No data