Objetivo The objective of the project is the comparative study of the primary structures of cell wall teichoic acids, phylogenetic relationships and numerous phenetic characteristics in a large group of Gram-positive bacteria of the order Actinomycetales with special focus on discovering new set of chemical markers of species and closely related genera. Particular attention will be paid to taxonomic study of novel and those groups of microorganisms where the current phenetic circumscriptions of species are confused, the species validity was not verified phylogenetically, and also plant pathogenic streptomycetes causing potato scabs.The partners are confident to obtaining experimental data which can be compiled to support their hypothesis that the primary structure of cell wall teichoic acids is a property of the highest value among other phenetic criteria in the delineation of actinomycete species and closely related genera. Structural studies of new teichoic acids and other anionic polymers are of special interest in view of the regulatory role of these polymers in biochemical processes occurring at surface regions of the prokaryotic cell and their role in virulence of plant pathogenic strains causing potato scabs. The primary structures of teichoic acids will be analysed by chemical methods and NMR spectroscopy. Consistency of the chemical and the NMR data ensures (in the present state of the art) a reliable identification of the primary structure examined. Taxonomic analyses will be made by using polyphasic approach to taxonomy and the respective modern methods.This collaborative research will result in comprehensive data on the primary structure of cell wall teichoic acids and some other anionic polymers and their distribution among different taxa of the order Actinomycetales, elucidation of species borders and providing new sets of chemical markers for emended circumscription of different actinomycete taxa of interest for medicine, biotechnology, ecology and food industry. It is anticipated that the study will reveal novel species and genera of actinomycetes and cell wall polymers, and new methods for identification of the causal agents of potato scab will be developed, that is important to elaborate efficient strategies to control. Means of species identification based on the NMR-spectra and the easy determinable structural elements of the polymers will be extremely useful in routine microbiological practice. Programa(s) IC-INTAS - International Association for the promotion of cooperation with scientists from the independent states of the former Soviet Union (INTAS), 1993- Tema(s) 4 - Life Sciences OPEN - OPEN Call Convocatoria de propuestas Data not available Régimen de financiación Data not available Coordinador DSMZ Aportación de la UE Sin datos Dirección Mascheroder Weg 1b 38124 Braunschweig Alemania Ver en el mapa Coste total Sin datos Participantes (5) Ordenar alfabéticamente Ordenar por aportación de la UE Ampliar todo Contraer todo Belarusian Research Institute for Potato Growing Bielorrusia Aportación de la UE Sin datos Dirección Kovaleva Street 2a 223013 Samokhvalovitchi, Minsk region Ver en el mapa Coste total Sin datos M.V. Lomonosov Moscow State University Rusia Aportación de la UE Sin datos Dirección Vorob'evy gory 119899 Moscow Ver en el mapa Coste total Sin datos Russian Academy of Sciences Rusia Aportación de la UE Sin datos Dirección Prospekt Nauki, 5 142290 Pushchino, Moscow Region Ver en el mapa Coste total Sin datos Russian Academy of Sciences Rusia Aportación de la UE Sin datos Dirección Leninsky prospect 47 117913 Moscow Ver en el mapa Coste total Sin datos Stockholm University Suecia Aportación de la UE Sin datos Dirección 10691 Stockholm Ver en el mapa Coste total Sin datos
