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Investigation of biochemical and genetical diversity of terpenoid biosynthesis for the production of high value-added compounds

Investigation of biochemical and genetical diversity of terpenoid biosynthesis for the production of high value-added compounds

Objective

Terrene syntheses are responsible for a key biosynthetic step in the formation of many mono- and sesquiterpenes produced by aromatic plants that are valuable in medicine, in food and in the cosmetic industry. The overall objective of the project is to exploit the natural diversity of expression of terrene syntheses to obtain a detailed understanding of the molecular and structural basis of terpenesynthase function, so enabling the informed development of strategies for producing important value-added trapezoids at high levels both in vivo and inviter. The terrene syntheses genes of three species will be cloned and expressed, the encoded enzymes characterised, and the role of these catalysts in producing diverse terrene profiles investigated. The elucidation of structure-function relationships within terrene syntheses families will provide the theoretical basis to develop the possibility of protein engineering.

Coordinator

UNIVERSITY OF VETERINARY MEDICINE VIENNA

Address

Veterinaerplatz 1
1210 Wien

Austria

Administrative Contact

Chlodwig FRANZ (Prof. Dr.)

Participants (6)

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AUSTRIA WIRTSCHAFTSSERVICE GESELLSCHAFT M.B.H

Austria

DR. JUNGHANNS GMBH

Germany

MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V.

Germany

MEDITERRANEAN AGRONOMIC INSTITUTE OF CHANIA

Greece

UNIVERSITY OF READING

United Kingdom

VIORYL CHEMICAL AND AGRICULTURAL INDUSTRY RESEARCH SA

Greece

Project information

Grant agreement ID: QLK3-CT-2002-01930

  • Start date

    1 December 2002

  • End date

    31 January 2006

Funded under:

FP5-LIFE QUALITY

  • Overall budget:

    € 1 408 547

  • EU contribution

    € 1 297 542

Coordinated by:

UNIVERSITY OF VETERINARY MEDICINE VIENNA

Austria