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European standard operating procedures for electrochemotherapy and electrogenetherapy

Objective

The objective of ESOPE is to validate the clinical applications of electroporation of cells in tissues and to establish standard operating procedures (SOP) for their standardised use and rapid dissemination in Europe. These applications are antitumor electrochemotherapy and electrogenetherapy (i.e. DNA electrotransfer in vivo for a new non viral gene therapy). The Project benefits from new EU equipment developed within the 5th PCRD, equipment designed to deliver only the electrical energy necessary to achieve in vivo electroporation, ensuring patient safety as well as the reliability and efficacy of in vivo drug and gene delivery. ESOPE project objectives will be achieved by:
1) controlled application of the treatments according to predefined guidelines;
2) evaluation of the procedures and of the results;
3) definition of SOP and
4) dissemination of these therapies by the preparation of educational and training material, the certification of teams, the organisation of a large meeting for users' information, and the establishment of appropriate contacts with national and EU regulatory agencies and health organisations.

Funding Scheme

DEM - Demonstration contracts

Coordinator

INSTITUT GUSTAVE ROUSSY

Participants (5)

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
France
Address
Rue Michel Ange 3
75794 Paris
HERLEV UNIVERSITET HOSPITAL
Denmark
Address
75, Herlev Ringvej
2730 Herlev
IGEA
Italy
Address
Viale Della Chimica , 21
41012 Carpi
INSTITUTE OF ONCOLOGY LJUBLJANA
Slovenia
Address
Zaloska 2
1105 Ljubljana
UNIVERSITY COLLEGE CORK, NATIONAL UNIVERSITY OF IRELAND, CORK
Ireland
Address
Western Road, Presentation Buildings
30 Cork