Objetivo HIV-l vaccines are urgently needed especially in developing nations. HIV vaccine study sites are needed in developing nations for more rapid development and deployment of vaccines. DNA plasmid vaccines are promising candidates - Their potency needs to be improved. The programme will explore various modes of increasing the immunogenicity of priming with plasmid DNA; intradermal injections, with GM-CSF as adjuvant, intramucosal injections and boosting with a Modified Vaccinia Ankara vector, MVA. Vaccines produced from subtypes appropriate for Tanzania will be used. A study site will be established in Dar es Salaam- The prerequisites for approval will be addressed on all levels, paving the way to future trials - Immunogenicity studies will continue in Dar es Salaam, with a focus on mucosal immunity and durability of the immune response. Ámbito científico natural sciencesbiological sciencesgeneticsDNAmedical and health sciencesbasic medicineimmunologymedical and health scienceshealth sciencesinfectious diseasesRNA virusesHIVmedical and health sciencesbasic medicinepharmacology and pharmacypharmaceutical drugsvaccines Programa(s) FP5-INCO 2 - Programme for research, technological development and demonstration on "Confirming the international role of Community research,1998-2002" Tema(s) 1.2.1.-1.4. - Research for development Convocatoria de propuestas Data not available Régimen de financiación CSC - Cost-sharing contracts Coordinador KAROLINSKA INSTITUTE Aportación de la UE Sin datos Dirección Ringwaegen, 52 11883 STOCKHOLM Suecia Ver en el mapa Coste total Sin datos Participantes (4) Ordenar alfabéticamente Ordenar por aportación de la UE Ampliar todo Contraer todo LUDWIG-MAXIMILIANS UNIVERSITY OF MUNICH Alemania Aportación de la UE Sin datos Dirección 5,Leopoldstrasse 5 80802 MUENCHEN Ver en el mapa Coste total Sin datos MUHIMBILI UNIVERSITY COLLEGE OF HEALTH SCIENCES Tanzania Aportación de la UE Sin datos Dirección Off United Nations Road, West Upanga DAR ES SALAAM Ver en el mapa Coste total Sin datos STOCKHOLM SOEDER HOSPITAL Suecia Aportación de la UE Sin datos Dirección Ringvaegen, 52 11883 STOCKHOLM Ver en el mapa Coste total Sin datos UNIVERSITY OF CAPE TOWN Sudáfrica Aportación de la UE Sin datos Dirección Anzio Road 7925 OBSERVATORY, CAPE TOWN Ver en el mapa Coste total Sin datos