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Characterisation of mycobacterium tuberculosis populations during infection: a longitudinal study on drug resistance development

Objetivo

Drug resistance arises in Mycobacterium tuberculosis (MTB) generally by mutation of chromosomal genes, but despite combined drug therapy the spread of multi-drug- resistant (MDR) strains is alarmingly increasing. The LONG-DRUG project is a longitudinal study, carried out in prisons and the civil society in an area with high MDR-TB prevalence, which aims to document the generation of multi drug resistant MTB strains through the use of novel molecular techniques. The combined use of a variety of techniques on longitudinally obtained samples and primary cultures will enable to generate clinically significant knowledge on the evolution of multi drug resistance in Mycobacterium.

Convocatoria de propuestas

Data not available

Régimen de financiación

CSC - Cost-sharing contracts

Coordinador

UNIVERSIT DEGLI STUDI DI SIENA
Aportación de la UE
Sin datos
Dirección
Via Bracci, 16
53100 SIENA
Italia

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Coste total
Sin datos

Participantes (8)