Cel This training network addresses the secretory pathway in plants with a special focus on proteins, their interactions with each other and other biomolecules, and the potential of this pathway for biotechnology. The network partners provide non-overlapping expertise in methods to elucidate bio-molecular interactions, ranging from genetic approaches via co-localisation to specific protein-protein interactions using the most advanced protocols. The aims are1) to understand receptor function and signal transduction controlling protein sorting and vesicle transport,2) the identification of novel sorting receptors and sorting mechanisms that are likely to be unique to the plant kingdom,3) the molecular characterisation of interactions between chaperones and their ligands.4) To study a group of products of the secretory pathway within a set of specific model system, elucidate their step-wise biosynthesis and transport, and the way in which manipulation of: the pathway is possible to redirect these molecules or to prevent turnover.5) The predicted spin-off from this work will firstly contribute to the fundamental insight into the secretory pathway of plants and, secondly, help to evaluate the potential of the secretory pathway for directed pathway engineering in order to maximise productivity in plants of heterologous proteins with high added value, such as human serum proteins, antibodies, or vaccines.Within the framework of this research programme, we aim to set the stage for contained plant fermentations in bioreactors with the help of small-scale feasibility studies. We believe this programme will be instrumental in the development of high capacity and cost effective production systems combined with environmentally save procedures, which is currently an important issue to re-gain public acceptance of biotechnological applications for plant cells. Dziedzina nauki engineering and technologyenvironmental biotechnologybioremediationbioreactorsnatural sciencesbiological sciencesbiochemistrybiomoleculesproteinsproteomicssocial scienceseconomics and businesseconomicsproduction economicsproductivitymedical and health sciencesbasic medicinepharmacology and pharmacypharmaceutical drugsvaccinesengineering and technologyindustrial biotechnologybioprocessing technologiesfermentation Program(-y) FP5-HUMAN POTENTIAL - Programme for research, technological development and demonstration on "Improving the human research potential and the socio-economic knowledge base" (1998-2002) Temat(-y) 1.4.1.-1.1. - Research Training Networks Zaproszenie do składania wniosków Data not available System finansowania NET - Research network contracts Koordynator UNIVERSITY OF LEEDS Wkład UE Brak danych Adres Woodhouse lane LS2 9JT Leeds Zjednoczone Królestwo Zobacz na mapie Koszt całkowity Brak danych Uczestnicy (6) Sortuj alfabetycznie Sortuj według wkładu UE Rozwiń wszystko Zwiń wszystko NATIONAL RESEARCH COUNCIL OF ITALY Włochy Wkład UE Brak danych Adres Via Bassini, 15 20133 MILANO Zobacz na mapie Koszt całkowity Brak danych THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE Zjednoczone Królestwo Wkład UE Brak danych Adres 80,Tennis Court Road, 80 CB2 1GA CAMBRIDGE Zobacz na mapie Koszt całkowity Brak danych UNIVERSITE DE NEUCHATEL Szwajcaria Wkład UE Brak danych Adres Rue Emile-Argand, 9 2007 NEUCHATEL Zobacz na mapie Koszt całkowity Brak danych UPPSALA UNIVERSITY Szwecja Wkład UE Brak danych Adres 3,Husargatan 3 Biomedicininska Centrum 751 23 Uppsala Zobacz na mapie Koszt całkowity Brak danych WAGENINGEN UNIVERSITY Niderlandy Wkład UE Brak danych Adres 11,Binnenhaven 11 6709 PD WAGENINGEN Zobacz na mapie Koszt całkowity Brak danych WEIZMANN INSTITUTE OF SCIENCE Izrael Wkład UE Brak danych Adres Herzl Street 2 76100 REHOVOT Zobacz na mapie Koszt całkowity Brak danych
