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Telomeres and radiosensitivity of individuals

Project information

Grant agreement ID: FIGH-CT-2002-00217

  • Start date

    1 January 2003

  • End date

    31 December 2005

Funded under:

FP5-EAECTP C

  • Overall budget:

    € 1 690 081

  • EU contribution

    € 1 000 000

Coordinated by:

COMMISSARIAT A L'ENERGIE ATOMIQUE

France

Objective

Risk estimate of radiation-induced cancer in human population is based on epidemiological data. Most extrapolations are limited by the lack of understanding of the mechanisms responsible for radiation carcinogenesis. The acquisition of knowledge on common genetic factors that might determine inter-individual differences in low dose cancer risk encounters similar limitations. During TELORAD Project, evidence is accumulating that telomeres may be involved in cellular and organismal responsesto IR. Mice lacking functional telomerase are radiosensitive. Ataxia telangiectasia, Fanconia patients are radiosensitive and show altered telomere maintenance. The major aim of TELOSENS consortiumis to work on a goal oriented project to be able to give a precise answer to the following question :ISTELOMERE HETEROGENEITY A PARAMETER OF INDIVIDUAL RADIOSENSITIVITY for short term effect?

Leaflet | Map data © OpenStreetMap contributors, Credit: EC-GISCO, © EuroGeographics for the administrative boundaries

Coordinator

COMMISSARIAT A L'ENERGIE ATOMIQUE

Address

Ctr Etudes Fontenay-Aux-Roses Ce-Far
92265 Fontenay Aux Roses

France

Participants (10)

AUTONOMOUS UNIVERSITY OF BARCELONA

Spain

BRUNEL UNIVERSITY

United Kingdom

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE

France

CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS

Spain

ECOLE NORMALE SUPERIEURE DE LYON

France

NATIONAL RESEARCH COUNCIL OF ITALY

Italy

SERVICIO GALEGO DE SAUDE - SERGAS

Spain

UNIVERSITA DEGLI STUDI DI PAVIA

Italy

UNIVERSITY OF AARHUS

Denmark

UNIVERSITY OF ESSEN

Germany

Project information

Grant agreement ID: FIGH-CT-2002-00217

  • Start date

    1 January 2003

  • End date

    31 December 2005

Funded under:

FP5-EAECTP C

  • Overall budget:

    € 1 690 081

  • EU contribution

    € 1 000 000

Coordinated by:

COMMISSARIAT A L'ENERGIE ATOMIQUE

France

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