Objetivo Considerable progress has been made in understanding the mechanisms of pollutant induced cell injury. This ranges from the direct action of pollutants, their activated metabolites or radicals on biological molecules such as deoxyribonucleic acid (DNA), proteins or membrane components. Disturbances at the molecular and supramolecular (eg membranes) levels lead to organelle and cellular dysfunction and these in turn contribute to tissue and organ impairment and failure of the digestive and reproductive systems. The findings presented in this report contribute to a mechanistic understanding of the processes of pollutant toxicity and cell injury in an important environmental sentinel organism, namely the marine mussel. Consequently, this enables us to interpret distress signals from these organisms in a more environmentally meaningful way and to start to direct our thinking towards the problems of causal mechanisms, thus strengthening the basis for the use of mussels as sentinels for biological impact. Ámbito científico natural sciencesbiological sciencesgeneticsDNAnatural sciencesbiological sciencesbiochemistrybiomoleculesproteins Programa(s) FP1-STIMULATION 1C - Plan (EEC) to stimulate European scientific and technical cooperation and interchange, 1985-1988 Tema(s) Data not available Convocatoria de propuestas Data not available Régimen de financiación CSC - Cost-sharing contracts Coordinador NERC Centre of Coastal and Marine Sciences Aportación de la UE Sin datos Dirección Prospect Place West Hoe PL1 3DH Plymouth Reino Unido Ver en el mapa Coste total Sin datos Participantes (2) Ordenar alfabéticamente Ordenar por aportación de la UE Ampliar todo Contraer todo UNIVERSITE DE BORDEAUX I Francia Aportación de la UE Sin datos Dirección Cours de la Libération 351 33405 TALENCE Ver en el mapa Coste total Sin datos Università degli Studi di Genova Italia Aportación de la UE Sin datos Dirección Viale Benedetto XV 3 16132 Genova Ver en el mapa Coste total Sin datos