Obiettivo Considerable progress has been made in understanding the mechanisms of pollutant induced cell injury. This ranges from the direct action of pollutants, their activated metabolites or radicals on biological molecules such as deoxyribonucleic acid (DNA), proteins or membrane components. Disturbances at the molecular and supramolecular (eg membranes) levels lead to organelle and cellular dysfunction and these in turn contribute to tissue and organ impairment and failure of the digestive and reproductive systems. The findings presented in this report contribute to a mechanistic understanding of the processes of pollutant toxicity and cell injury in an important environmental sentinel organism, namely the marine mussel. Consequently, this enables us to interpret distress signals from these organisms in a more environmentally meaningful way and to start to direct our thinking towards the problems of causal mechanisms, thus strengthening the basis for the use of mussels as sentinels for biological impact. Campo scientifico natural sciencesbiological sciencesgeneticsDNAnatural sciencesbiological sciencesbiochemistrybiomoleculesproteins Programma(i) FP1-STIMULATION 1C - Plan (EEC) to stimulate European scientific and technical cooperation and interchange, 1985-1988 Argomento(i) Data not available Invito a presentare proposte Data not available Meccanismo di finanziamento CSC - Cost-sharing contracts Coordinatore NERC Centre of Coastal and Marine Sciences Contributo UE Nessun dato Indirizzo Prospect Place West Hoe PL1 3DH Plymouth Regno Unito Mostra sulla mappa Costo totale Nessun dato Partecipanti (2) Classifica in ordine alfabetico Classifica per Contributo UE Espandi tutto Riduci tutto UNIVERSITE DE BORDEAUX I Francia Contributo UE Nessun dato Indirizzo Cours de la Libération 351 33405 TALENCE Mostra sulla mappa Costo totale Nessun dato Università degli Studi di Genova Italia Contributo UE Nessun dato Indirizzo Viale Benedetto XV 3 16132 Genova Mostra sulla mappa Costo totale Nessun dato