Objective HIRA biochemical characterization including its possible partners to examine its physiological relevance in nucleoside assembly mechanisms in vitro. Producing recombinant Venous CENP-A and polyclinic antibodies against such protein, I will examine by immunofluorescence the possible role of HIRA in chromatin assembly that could be involved in the centromeric structure. Fields of science natural sciencesbiological sciencesbiochemistrybiomoleculesproteins Programme(s) FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002 Topic(s) 1.1.1.-4. - Key action Environment and Health Call for proposal Data not available Funding Scheme RGI - Research grants (individual fellowships) Coordinator INSTITUT CURIE EU contribution No data Address Rue d'Ulm 26 75248 PARIS France See on map Total cost No data