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Biodegradable bone glue for skeletal repair

Objectif

A large number of implant is available for osseous repair, and fresh autogenous bone grafts are preferred because of their compatibility. However there are several disadvantages associated with the use of autogenous bone, especially due to the limited supply at any one donor site and the added morbidity associated with its harvest (wound problems, permanent sensory loss...). This project aims to develop a new polyurethane polymer as a hard tissue adhesive for fractured bone The new biomaterial will ensure a best security compared with current procedures, as it eliminates the risk of transmission diseases due to foreign bone and the drawbacks linked to multi-chirurgical procedures.
The following R&D actions will be carried out:
- To examine that the biomaterial comes into contact with tissues and biological fluids
- To ensure that the repositioned bone fragments adhered well to their original sites
- To develop a controllable degradative process: study of the mode of degradation and excretion of the biomaterial
- To promote bone reconstruction (osteoinduction). It will be also necessary to develop a new approach, procedures and surgery technique.

Appel à propositions

Data not available

Régime de financement

EAW - Exploratory awards

Coordinateur

CURASAN PHARMA GMBH
Contribution de l’UE
Aucune donnée
Adresse
Lindigstrasse 4
63801 KLEINOSTHEIM
Allemagne

Voir sur la carte

Coût total
Aucune donnée

Participants (1)