Obiettivo This research proposal is comprehensive, encompassing all the complementary aspects necessary for the development of intervention strategies, including vaccination, immunotherapy, and antivirals to protect against SARS. In addition, techniques and materials will be generated to develop diagnostic kits that will lead to the identification of infected individuals at very early steps of the disease, and to differentiate between vaccinated and naturally infected people. The first focus of the project is vaccine development. Accordingly, a set of complementary strategies is proposed to guarantee the success. These strategies include "classical" vaccines (such as whole inactivated virus), subunit vaccines, and state of the art-recombinant technology derived vaccines. The second focus of the project is on the state of the art-therapeutic approaches, ranging from the use of monoclonal antibodies to specific antivirals. For achieving the primary objectives of this project, the availability of an adequate preclinical setting for SARS-CoV research, including animal models, as well as the access to relevant clinical samples are absolute preconditions. These all met in this project, as a result of the expertise of the individual groups involved. To develop this comprehensive project, laboratories from the European Union and China are collaborating. The laboratories from EU member states (Spain, UK, and The Netherlands), have a long term experience (more than twenty years) in coronavirus pathology, immunology and molecular biology. The groups from China have key knowledge on the onset and evolution of SARS, high technology, and have generated large collections of biological materials: viruses, sera, tissues, clinical and epidemiological data. Campo scientifico medical and health scienceshealth sciencesinfectious diseasesRNA virusescoronavirusesmedical and health sciencesbasic medicinepharmacology and pharmacypharmaceutical drugsvaccinesmedical and health sciencesbasic medicineimmunologyimmunotherapy Parole chiave Antivirais Diagnostics Immunotherapy SARS-CoV Vaccine Programma(i) FP6-POLICIES - Policy support: Specific activities covering wider field of research under the Focusing and Integrating Community Research programme 2002-2006. Argomento(i) POLICIES-2.2 - Public health issues, including epidemiology contributing to disease prevention and responses to emerging rare and communicable diseases, allergies, procedures for secure blood and organ donations, non-animal test methods Invito a presentare proposte FP6-2003-SSP-2-SARS Vedi altri progetti per questo bando Meccanismo di finanziamento STIP - Specific Targeted Innovation Project Coordinatore CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS Contributo UE Nessun dato Indirizzo Serrano, 117 MADRID Spagna Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato Partecipanti (9) Classifica in ordine alfabetico Classifica per Contributo UE Espandi tutto Riduci tutto INSTITUTE OF GENETICS AND DEVELOPMENTAL BIOLOGY, CHINESE ACADEMY OF SCIENCES Cina Contributo UE Nessun dato Indirizzo Datun Road, Anding Menwai BEIJING Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato UTRECHT UNIVERSITY, FACULTY OF VETERINARY MEDICINE Paesi Bassi Contributo UE Nessun dato Indirizzo Yalelaan 1 80.165 UTRECHT Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato INSTITUTE FOR ANIMAL HEALTH Regno Unito Contributo UE Nessun dato Indirizzo High Street Compton COMPTON, NEWBURY Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato ERASMUS MC Paesi Bassi Contributo UE Nessun dato Indirizzo Dr. Molewaterplein 50 1738 ROTTERDAM Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato LABORATORY OF MOLECULAR MEDICINE, COLLEGE OF LIFE SCIENCES, SUN YATSEN UNIVERSITY, GUANGZHOU, CHINA Cina Contributo UE Nessun dato Indirizzo 135 West XinGang Road GUANGZHOU Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato WUHAN INSTITUTE OF VIROLOGY, CHINESE ACADEMY OF SCIENCES Cina Contributo UE Nessun dato Indirizzo Xiaohongsan 44# WUHAN Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato INSTITUTO DE SALUD CARLOS III Spagna Contributo UE Nessun dato Indirizzo Siensio delgado, 4-6 MADRID Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato FORT DODGE VETERINARIA SA Spagna Contributo UE Nessun dato Indirizzo CARRETERA CAMPRODON S/N FINCA OLOT-49 VALL DE BIANYA Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato INTERVET UK LTD Regno Unito Contributo UE Nessun dato Indirizzo Walton Manor, Walton MILTON KEYNES Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato
