Objetivo Heart failure caused by the ischaemic heart disease is one of the most common causes of morbidity an mortality across Europe, especially high among elderly people, but the post-infarction myocardial injury is also major cause of disability in younger survi vors from myocardial infarction. The proposed project is dedicated to stimulate "state-of-the-art" research on the clinical applications of autologous stem cells, including bone marrow derived stem cells as well as myoblasts, to the regeneration of heart m uscle in irreversibly damaged post- infarction regions. The consortium includes most experienced European clinical researchers in the field, which already had accomplished the phase I clinical trials in participating centres. The researchers from participa ting centres have agreed to coordinate their future clinical trials on stem cell transplantation for myocardial regeneration in patients with postinfarction heart failure, as a result of the proposed project. This will include analysis of polled clinical d ata obtained in participating centres, reciprocal exchange of information on cell culture and cell preparation for transplantation. This will also include standardization of clinical protocols aiming at evaluation of the clinical efficacy of myocardial rep lacement therapy as well as hand-on training of different techniques of cell delivery, including percutaneous cell transplantations, in particular trans-coronary arteries bone marrow stem cell delivery protocols as well as trans- ventricular and trans-card iac-veins myoblast injection techniques. As a result of further integration of the consortium, it is expected to stimulate formation of a common future phase III studies at international level, especially with an option of submitting future Integrated Proj ect application within the 6th Framework Programme. Ámbito científico social sciencessociologydemographymortalitymedical and health sciencesmedical biotechnologycells technologiesstem cellsmedical and health sciencesclinical medicinecardiologymedical and health sciencesclinical medicinetransplantation Palabras clave Stem cells cell therapy organ regeneration Programa(s) FP6-LIFESCIHEALTH - Life sciences, genomics and biotechnology for health: Thematic Priority 1 under the Focusing and Integrating Community Research programme 2002-2006. Tema(s) LSH-2003-2.1.0-2 - Coordination of clinical trials in Europe LSH-2003-3-3 - Promotion of cooperation with Associated Candidate Countries Convocatoria de propuestas FP6-2003-LIFESCIHEALTH-I Consulte otros proyectos de esta convocatoria Régimen de financiación SSA - Specific Support Action Coordinador UNIVERSITY SCHOOL OF MEDICAL SCIENCES Aportación de la UE Sin datos Dirección Ui. fredry 10 Poznan Polonia Ver en el mapa Enlaces Sitio web Opens in new window Coste total Sin datos Participantes (8) Ordenar alfabéticamente Ordenar por aportación de la UE Ampliar todo Contraer todo HOPITAL EUROPEEN GEORGES POMPIDOU Francia Aportación de la UE Sin datos Dirección 20, rue leblanc Paris Ver en el mapa Coste total Sin datos UNIVERSITY OF VALLADOLLID España Aportación de la UE Sin datos Dirección Ramon y cajal 3 Valladolid Ver en el mapa Coste total Sin datos UNIVERSITY OF ROSTOCK Alemania Aportación de la UE Sin datos Dirección Schilligallee 35 Rostock Ver en el mapa Enlaces Sitio web Opens in new window Coste total Sin datos CHARLES UNIVERSITY PRAGUE Chequia Aportación de la UE Sin datos Dirección Ruska 87 Prague Ver en el mapa Enlaces Sitio web Opens in new window Coste total Sin datos UNIVERSITY HOSPITAL, CLERMONT-FERRAND Francia Aportación de la UE Sin datos Dirección Rue montalembert Clermont-ferrand Ver en el mapa Coste total Sin datos VILNIUS UNIVERSITY Lituania Aportación de la UE Sin datos Dirección Santariskiu str. 2 Vilnius Ver en el mapa Enlaces Sitio web Opens in new window Coste total Sin datos POLISH ACADEMY OF SCIENCES Polonia Aportación de la UE Sin datos Dirección Strzeszynska 32 Poznan Ver en el mapa Enlaces Sitio web Opens in new window Coste total Sin datos ERASMUS UNIVERSITY ROTTERDAM Países Bajos Aportación de la UE Sin datos Dirección Drmolewaterplein 40 Rotterdam Ver en el mapa Enlaces Sitio web Opens in new window Coste total Sin datos