Obiettivo Heart failure caused by the ischaemic heart disease is one of the most common causes of morbidity an mortality across Europe, especially high among elderly people, but the post-infarction myocardial injury is also major cause of disability in younger survi vors from myocardial infarction. The proposed project is dedicated to stimulate "state-of-the-art" research on the clinical applications of autologous stem cells, including bone marrow derived stem cells as well as myoblasts, to the regeneration of heart m uscle in irreversibly damaged post- infarction regions. The consortium includes most experienced European clinical researchers in the field, which already had accomplished the phase I clinical trials in participating centres. The researchers from participa ting centres have agreed to coordinate their future clinical trials on stem cell transplantation for myocardial regeneration in patients with postinfarction heart failure, as a result of the proposed project. This will include analysis of polled clinical d ata obtained in participating centres, reciprocal exchange of information on cell culture and cell preparation for transplantation. This will also include standardization of clinical protocols aiming at evaluation of the clinical efficacy of myocardial rep lacement therapy as well as hand-on training of different techniques of cell delivery, including percutaneous cell transplantations, in particular trans-coronary arteries bone marrow stem cell delivery protocols as well as trans- ventricular and trans-card iac-veins myoblast injection techniques. As a result of further integration of the consortium, it is expected to stimulate formation of a common future phase III studies at international level, especially with an option of submitting future Integrated Proj ect application within the 6th Framework Programme. Campo scientifico social sciencessociologydemographymortalitymedical and health sciencesmedical biotechnologycells technologiesstem cellsmedical and health sciencesclinical medicinecardiologymedical and health sciencesclinical medicinetransplantation Parole chiave Stem cells cell therapy organ regeneration Programma(i) FP6-LIFESCIHEALTH - Life sciences, genomics and biotechnology for health: Thematic Priority 1 under the Focusing and Integrating Community Research programme 2002-2006. Argomento(i) LSH-2003-2.1.0-2 - Coordination of clinical trials in Europe LSH-2003-3-3 - Promotion of cooperation with Associated Candidate Countries Invito a presentare proposte FP6-2003-LIFESCIHEALTH-I Vedi altri progetti per questo bando Meccanismo di finanziamento SSA - Specific Support Action Coordinatore UNIVERSITY SCHOOL OF MEDICAL SCIENCES Contributo UE Nessun dato Indirizzo Ui. fredry 10 Poznan Polonia Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato Partecipanti (8) Classifica in ordine alfabetico Classifica per Contributo UE Espandi tutto Riduci tutto HOPITAL EUROPEEN GEORGES POMPIDOU Francia Contributo UE Nessun dato Indirizzo 20, rue leblanc Paris Mostra sulla mappa Costo totale Nessun dato UNIVERSITY OF VALLADOLLID Spagna Contributo UE Nessun dato Indirizzo Ramon y cajal 3 Valladolid Mostra sulla mappa Costo totale Nessun dato UNIVERSITY OF ROSTOCK Germania Contributo UE Nessun dato Indirizzo Schilligallee 35 Rostock Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato CHARLES UNIVERSITY PRAGUE Cechia Contributo UE Nessun dato Indirizzo Ruska 87 Prague Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato UNIVERSITY HOSPITAL, CLERMONT-FERRAND Francia Contributo UE Nessun dato Indirizzo Rue montalembert Clermont-ferrand Mostra sulla mappa Costo totale Nessun dato VILNIUS UNIVERSITY Lituania Contributo UE Nessun dato Indirizzo Santariskiu str. 2 Vilnius Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato POLISH ACADEMY OF SCIENCES Polonia Contributo UE Nessun dato Indirizzo Strzeszynska 32 Poznan Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato ERASMUS UNIVERSITY ROTTERDAM Paesi Bassi Contributo UE Nessun dato Indirizzo Drmolewaterplein 40 Rotterdam Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato