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Dendritic cells for novel immmunotherapies

Objective

Dendritic cell (DC) immune-biology has enormous potential for development of new immunotherapies for cancer and infectious disease. Europe possesses a critical mass of leaders in the field who have pioneered many innovative advances and provided initial pr oof of principle for the approach. This NoE, DC-THERA, will integrate the activities of 25 participant groups of scientists and clinicians and 6 high quality SMEs across Europe. It will incorporate additional groups, particularly from future member states, as Associated Members of the Network Their collective expertise and resources will be forged into an ambitious Joint Programme of Activities to restructure the field. It will translate genomic, proteomic and bioinformatic information, with knowledge from molecular cell biology and pre-clinical models, into therapeutic endpoints: clinical trials of DC-based therapies for cancer and HIV. Towards this end, four thematic S&T Clusters have been defined, with a fifth for horizontal activities. The latter inc ludes development of synergistic links with other Networks, providing added value to EC Programmes by underpinning all projects developing new vaccine strategies for major killer diseases. The Network will implement an IT-based integrated knowledge managem ent system and provide a centralised European resource of databases for the field. DC-THERA will develop new research tools, integrate existing and new technological platforms, recruit additional support staff, and make these available as shared resources for all partners It will implement an ambitious Education and Training Programme, including new PhD studentships, a Visiting Scholars Scheme, high quality training courses, and a postgraduate degree in translational DC immunobiology. DC-THERA will contribu te to the European biotechnology sector and have a major impact on European policy-making for the future. DC-THERA will evolve itself into a Centre of Excellence for DC Biology,with a lasting and global impact.

Call for proposal

FP6-2003-LIFESCIHEALTH-I
See other projects for this call

Funding Scheme

NoE - Network of Excellence

Coordinator

THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
Address
University Offices, Wellington Square
Oxford
United Kingdom

Participants (31)

STICHTING KATHOLIEKE UNIVERSITEIT, THE UNIVERSITY MEDICAL CENTRE NIJMEGEN
Netherlands
Address
Geert Grooteplein 10
Nijmegen
MEDICAL RESEARCH COUNCIL
United Kingdom
Address
Mrc Head Office, 20 Park Crescent
London
UNIVERSITY OF MILANO-BICOCCA
Italy
Address
Piazza Dell'ateneo Nuovo,1
Milan
BIOVEX LTD
United Kingdom
Address
Milton Park 70
Oxford
BRUCELLS SA
Belgium
Address
Av Joseph Wybran, 40
Brussels
CHIRON S.R.L.
Italy
Address
Via Fiorentina 1
Siena
LEAF BIOSCIENCE S.R.L.
Italy
Address
Via Puccini, 3
Milan
ARGOS THERAPEUTICS, INC
United States
Address
4233 Technology Drive
Durham, Nc
SEKMED S.R.L.
Italy
Address
Corso Magenta 31
Milano
INSTITUT CURIE
France
Address
26, Rue D'ulm'
Paris
CHRISTIAN DE DUVE INSTITUTE OF CELLULAR PATHOLOGY
Belgium
Address
Avenue Hippocrate, 75
Brussels
UNIVERSITA' DEGLI STUDI DI FIRENZE', DIPARTIMENTO DI FARMACOLOGIA
Italy
Address
Piazza San Marco 4
Firenze
KAROLINSKA INSTITUTET
Sweden
Address
Nobels Väg 5
Stockholm
LEIDEN UNIVERSITY MEDICAL CENTER
Netherlands
Address
Albinusdreef 2
Leiden
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
France
Address
3 Rue Michel-ange
Marseille
FONDAZIONE CENTRO SAN RAFFAELE DEL MONTE TABOR
Italy
Address
Via Olgettina 60
Milan
DEUTSCHES RHEUMA-FORSCHUNGSZENTRUM BERLIN
Germany
Address
Schumannstrasse 21-22
Berlin
CANCER RESEARCH UK
United Kingdom
Address
44 Lincoln's Inn Fields'
London
INSTITUTE FOR RESEARCH IN BIOMEDICINE
Switzerland
Address
Via Vincenzo Vela 6
Bellinzona
UNIVERSITY OF ZURICH
Switzerland
Address
Winterthurerstrasse 266A
Zurich
VRIJE UNIVERSITEIT BRUSSEL
Belgium
Address
Pleinlaan 2
Brussels
TECHNISCHE UNIVERSITAET MUENCHEN
Germany
Address
Arcisstrasse 21
Muenchen
INSTITUT GUSTAVE ROUSSY
France
Address
39 Rue Camille Desmoulins
Villejuif
GENOPOLIS - CONSORTIUM FOR FUNCTIONAL GENOMICS
Italy
Address
Piazza Della Scienza, 4
Milan
MAX PLANCK GESELLSCHAFT ZUR FOERDUNG DER WISSENSCHAFT E.V., REPRESENTED BY MAX PLANCK INSTITUTE OF BIOCHEMISTRY
Germany
Address
Am Klopferspitz
Martinsried
HUMANITAS MIRASOLE SPA
Italy
Address
Via Manzoni, 56
Rozzano, Milan
FRIEDRICH ALEXANDER UNIVERSITÄT ERLANGEN-NÜRNBERG
Germany
Address
Schlossplatz 4
Erlangen
INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE
France
Address
101 Rue De Tolbiac
Paris
ISTITUTO SUPERIORE DI SANITÀ
Italy
Address
Viale Regina Elena 299
Rome
UNIVERSITÉ LIBRE DE BRUXELLES
Belgium
Address
Avenue F.d. Roosevelt 50
Bruxelles
UNIVERSITÉ RENÉ DESCARTES
France
Address
12, Rue De L'ecole De Medecine
Paris